1 | 7QQX|1|A+ 7QQX|1|C+ 7QQX|1|D (rep) | Trans-activating crRNA | FANCF off-target5 non-target strand, FANCF off-target5 target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF off-target5 DNA substrate | X-ray diffraction | 2.4 | 123 | 2022-10-26 |
2 | 7QQS|1|A+ 7QQS|1|C+ 7QQS|1|D | Trans-activating crRNA | FANCF on-target non-target strand, FANCF on-target target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF on-target DNA substrate | X-ray diffraction | 2.4 | 123 | 2022-10-26 |
3 | 7QQU|1|A+ 7QQU|1|C+ 7QQU|1|D | Trans-activating crRNA | FANCF off-target2 non-target strand, FANCF off-target2 target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF off-target2 DNA substrate | X-ray diffraction | 2.45 | 123 | 2022-10-26 |
4 | 7QQT|1|A+ 7QQT|1|C+ 7QQT|1|D | Trans-activating crRNA | FANCF off-target1 non-target strand, FANCF off-target1 target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF off-target1 DNA substrate | X-ray diffraction | 2.5 | 123 | 2022-10-26 |
5 | 7QQW|1|A+ 7QQW|1|C+ 7QQW|1|D | Trans-activating crRNA | FANCF off-target4 non-target strand, FANCF off-target4 target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF off-target4 DNA substrate | X-ray diffraction | 3.1 | 118 | 2022-10-26 |
6 | 7QQZ|1|A+ 7QQZ|1|C+ 7QQZ|1|D | Trans-activating crRNA | FANCF off-target7 non-target strand, FANCF off-target7 target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF off-target7 DNA substrate | X-ray diffraction | 2.25 | 122 | 2022-10-26 |
7 | 7QR5|1|A+ 7QR5|1|C+ 7QR5|1|D | Trans-activating crRNA | FANCF off-target6 non-target strand, FANCF off-target6 target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF off-target6 DNA substrate | X-ray diffraction | 3.3 | 123 | 2022-10-26 |
8 | 7QQV|1|A+ 7QQV|1|C+ 7QQV|1|D | Trans-activating crRNA | FANCF off-target3 non-target strand, FANCF off-target3 target strand, FANCF sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to FANCF off-target3 DNA substrate | X-ray diffraction | 2.25 | 123 | 2022-10-26 |