1 | 6JDV|1|B+ 6JDV|1|C+ 6JDV|1|D (rep) | CRISPR RNA direct repeat element | non-target DNA strand, sgRNA, target DNA strand | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic state | X-ray diffraction | 3.1 | 189 | 2019-11-06 |
2 | 6JE4|1|F+ 6JE4|1|G+ 6JE4|1|H | CRISPR RNA direct repeat element | non-target DNA strand, sgRNA, target DNA strand | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | X-ray diffraction | 3.07 | 185 | 2019-11-06 |
3 | 6KC8|1|B+ 6KC8|1|C+ 6KC8|1|P+ 6KC8|1|D | CRISPR RNA direct repeat element | DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*A)-3'), DNA (5'-D(P*AP*AP*GP*TP*TP*AP*AP*AP*TP*AP*GP*CP*AP*GP*AP*GP*TP*GP*AP*CP*C)-3'), sgRNA | synthetic construct | Synthetic | RF01344 | Crystal structure of WT Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in post-cleavage state | X-ray diffraction | 2.9 | 176 | 2019-11-06 |
4 | 6JE4|1|L+ 6JE4|1|M+ 6JE4|1|N | CRISPR RNA direct repeat element | non-target DNA strand, sgRNA, target DNA strand | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | X-ray diffraction | 3.07 | 186 | 2019-11-06 |
5 | 6JE4|1|P+ 6JE4|1|Q+ 6JE4|1|R | CRISPR RNA direct repeat element | non-target DNA strand, sgRNA, target DNA strand | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | X-ray diffraction | 3.07 | 183 | 2019-11-06 |
6 | 6JE3|1|B+ 6JE3|1|C+ 6JE3|1|D | CRISPR RNA direct repeat element | non-target DNA strand, sgRNA, target DNA strand | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhang | X-ray diffraction | 2.93 | 165 | 2019-11-06 |
7 | 6JE4|1|B+ 6JE4|1|C+ 6JE4|1|D | CRISPR RNA direct repeat element | non-target DNA strand, sgRNA, target DNA strand | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | X-ray diffraction | 3.07 | 182 | 2019-11-06 |
8 | 6JFU|1|B+ 6JFU|1|C+ 6JFU|1|D | CRISPR RNA direct repeat element | non-target strand, sgRNA, target-strand DNA | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) | X-ray diffraction | 3.2 | 151 | 2019-11-06 |
9 | 6KC7|1|B+ 6KC7|1|C+ 6KC7|1|D | CRISPR RNA direct repeat element | DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*AP*AP*AP*GP*TP*T)-3'), sgRNA | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in seed-base paring state | X-ray diffraction | 3.3 | 141 | 2019-11-06 |
10 | 6JE9|1|B | CRISPR RNA direct repeat element | sgRNA | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | X-ray diffraction | 3.46 | 115 | 2019-11-06 |
11 | 6JE9|1|D | CRISPR RNA direct repeat element | sgRNA | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | X-ray diffraction | 3.46 | 113 | 2019-11-06 |
12 | 6JDQ|1|B | CRISPR RNA direct repeat element | sgRNA | synthetic construct | Synthetic | RF01344 | Crystal structure of Nme1Cas9 in complex with sgRNA | X-ray diffraction | 2.95 | 117 | 2019-11-06 |