#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.672023-04-19
28A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.672023-03-08
38G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.292023-04-19
47XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.52023-04-05
56ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.62020-08-19
67OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.22022-10-05
76ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.72020-07-29
88G60|1|L5+ 8G60|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)Electron microscopy2.542023-04-19
97XNX|1|L1+ 7XNX|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsElectron microscopy2.72023-04-05
108G5Z|1|L5+ 8G5Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)Electron microscopy2.642023-04-19
117F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.722022-06-22
128FL3|1|L3+ 8FL3|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I2)Electron microscopy2.532023-07-12
136Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.82020-07-08
146Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.92020-07-29
158FLE|1|L3+ 8FLE|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L2)Electron microscopy2.482023-07-12
168FLB|1|L3+ 8FLB|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K2)Electron microscopy2.552023-07-12
178FL7|1|L3+ 8FL7|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J2)Electron microscopy2.552023-07-12
188G6J|1|L5+ 8G6J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)Electron microscopy2.82023-04-19
196QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.92019-04-24
206ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy32020-08-12
216Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy32020-07-29
227QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
238FLD|1|L3+ 8FLD|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L1)Electron microscopy2.582023-07-12
248FL6|1|L3+ 8FL6|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J1)Electron microscopy2.622023-07-12
258FLA|1|L3+ 8FLA|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K1)Electron microscopy2.632023-07-12
268FL2|1|L3+ 8FL2|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I1)Electron microscopy2.672023-07-12
277QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
288IDT|1|2+ 8IDT|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State GElectron microscopy2.82023-08-09
296XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.82020-10-07
306ZMO|1|L5+ 6ZMO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexElectron microscopy3.12020-08-19
316Z6M|1|L5+ 6Z6M|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1Electron microscopy3.12020-07-29
328FLF|1|L3+ 8FLF|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L3)Electron microscopy2.652023-07-12
338G61|1|L5+ 8G61|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)Electron microscopy2.942023-04-19
348INF|1|2+ 8INF|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State F'Electron microscopy32023-08-09
358IDY|1|2+ 8IDY|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State FElectron microscopy32023-08-09
368FL9|1|L3+ 8FL9|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J3)Electron microscopy2.752023-07-12
378FLC|1|L3+ 8FLC|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K3)Electron microscopy2.762023-07-12
386OLE|1|t+ 6OLE|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
396OM0|1|t+ 6OM0|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
406Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy32020-04-15
418FL4|1|L3+ 8FL4|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I3)Electron microscopy2.892023-07-12
426LQM|1|2+ 6LQM|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state CElectron microscopy3.092020-08-26
436Y0G|1|L5+ 6Y0G|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in classical-PRE stateElectron microscopy3.22020-04-15
447BHP|1|L5+ 7BHP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human Ebp1 - 80S ribosomeElectron microscopy3.32021-02-03
456LU8|1|2+ 6LU8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a human pre-60S ribosomal subunit - state AElectron microscopy3.132020-08-26
466LSR|1|2+ 6LSR|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state BElectron microscopy3.132020-08-26
478INE|1|2+ 8INE|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State G'Electron microscopy3.22023-08-09
488INK|1|2+ 8INK|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State DElectron microscopy3.22023-08-09
498IPY|1|2+ 8IPY|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State D'Electron microscopy3.22023-08-09
508IPD|1|2+ 8IPD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State CElectron microscopy3.22023-08-09
516LSS|1|2+ 6LSS|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state preAElectron microscopy3.232020-08-26
528IE3|1|2+ 8IE3|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State EElectron microscopy3.32023-08-09
538FKY|1|L3+ 8FKY|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State F)Electron microscopy2.672023-07-12
546OLI|1|t+ 6OLI|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)Electron microscopy3.52019-06-19
556OLG|1|A2+ 6OLG|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)Electron microscopy3.42019-06-19
568FKW|1|L3+ 8FKW|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D2)Electron microscopy2.52023-07-12
578IR1|1|2+ 8IR1|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRMAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State AElectron microscopy3.32023-08-09
588FKV|1|L3+ 8FKV|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D1)Electron microscopy2.472023-07-12
598IR3|1|2+ 8IR3|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State B'Electron microscopy3.52023-08-09
606Y57|1|L5+ 6Y57|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in hybrid-PRE stateElectron microscopy3.52020-04-15
618FKX|1|L3+ 8FKX|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State E)Electron microscopy2.592023-07-12
625T2C|1|A+ 5T2C|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CryoEM structure of the human ribosome at 3.6 Angstrom resolutionElectron microscopy3.62017-01-25
638FKZ|1|L3+ 8FKZ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State G)Electron microscopy3.042023-07-12
646OM7|1|t+ 6OM7|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsElectron microscopy3.72019-06-19
654UG0|1|L5+ 4UG0|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002STRUCTURE OF THE HUMAN 80S RIBOSOMEElectron microscopy3.62015-06-10
666OLF|1|t+ 6OLF|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsElectron microscopy3.92019-06-19
676W6L|1|t+ 6W6L|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human ribosome-TMCO1 transloconElectron microscopy3.842020-09-02
688FKU|1|L3+ 8FKU|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C2)Electron microscopy2.822023-07-12
698FKT|1|L3+ 8FKT|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C1)Electron microscopy2.812023-07-12
706IP5|1|1A+ 6IP5|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)Electron microscopy3.92019-05-29
716IP8|1|1A+ 6IP8|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)Electron microscopy3.92019-05-29
726OLZ|1|A2+ 6OLZ|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAElectron microscopy3.92019-06-19
738BF9|1|5Large subunit ribosomal RNARNA (1766)Ovis ariesEukaryaRF02543Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.Electron microscopy2.692023-11-01
745AJ0|1|A2+ 5AJ0|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo electron microscopy of actively translating human polysomes (POST state).Electron microscopy3.52015-05-20
758FKS|1|L3+ 8FKS|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B2)Electron microscopy2.882023-07-12
768FKR|1|L3+ 8FKR|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B1)Electron microscopy2.892023-07-12
778FKQ|1|L3+ 8FKQ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A2)Electron microscopy2.762023-07-12
788FKP|1|L3+ 8FKP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A1)Electron microscopy2.852023-07-12
798IPX|1|2+ 8IPX|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State C'Electron microscopy4.32023-08-09
808FL0|1|L3Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human nucleolar pre-60S ribosomal subunit (State H)Electron microscopy2.912023-07-12
815LKS|1|L5+ 5LKS|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure-function insights reveal the human ribosome as a cancer target for antibioticsElectron microscopy3.62017-04-26
826IP6|1|1A+ 6IP6|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)Electron microscopy4.52019-05-29
834V6X|1|A5+ 4V6X|1|A8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the human 80S ribosomeElectron microscopy52014-07-09
846SXO|1|L5Large subunit ribosomal RNA28S ribosomal RNA including ES27L-B (2839-3265)Homo sapiensEukaryaRF02543Cryo-EM structure of the human Ebp1-ribosome complexElectron microscopy3.32020-02-19
857ZFW|1|L5Large subunit ribosomal RNARNA (615-MER)Homo sapiensEukaryaRF02543Structure of human 80S ribosome obtained from ssDNA coated gridElectron microscopy3.82022-11-23
865A8L|1|ALarge subunit ribosomal RNA28S RIBOSOMAL RNAHomo sapiensEukaryaRF02543Human eRF1 and the hCMV nascent peptide in the translation termination complexElectron microscopy3.82015-12-02

Release history

Release3.3073.3083.3093.3103.311
Date2023-11-012023-11-082023-11-152023-11-242023-11-29

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_all_65061.22NR_all_65061.213.307(85) 4UG0|1|L5+4UG0|1|L8, 4V6X|1|A5+4V6X|1|A8, 5A8L|1|A, 5AJ0|1|A2+5AJ0|1|A3, 5LKS|1|L5+5LKS|1|L8, 5T2C|1|A+5T2C|1|C, 6IP5|1|1A+6IP5|1|1C, 6IP6|1|1A+6IP6|1|1C, 6IP8|1|1A+6IP8|1|1C, 6LQM|1|2+6LQM|1|8, 6LSR|1|2+6LSR|1|8, 6LSS|1|2+6LSS|1|8, 6LU8|1|2+6LU8|1|8, 6OLE|1|t+6OLE|1|D, 6OLF|1|t+6OLF|1|D, 6OLG|1|A2+6OLG|1|A3, 6OLI|1|t+6OLI|1|D, 6OLZ|1|A2+6OLZ|1|A3, 6OM0|1|t+6OM0|1|D, 6OM7|1|t+6OM7|1|D, 6QZP|1|L5+6QZP|1|L8, 6SXO|1|L5, 6W6L|1|t+6W6L|1|D, 6XA1|1|L5+6XA1|1|L8, 6Y0G|1|L5+6Y0G|1|L8, 6Y2L|1|L5+6Y2L|1|L8, 6Y57|1|L5+6Y57|1|L8, 6Y6X|1|L5+6Y6X|1|L8, 6Z6L|1|L5+6Z6L|1|L8, 6Z6M|1|L5+6Z6M|1|L8, 6Z6N|1|L5+6Z6N|1|L8, 6ZM7|1|L5+6ZM7|1|L8, 6ZME|1|L5+6ZME|1|L8, 6ZMI|1|L5+6ZMI|1|L8, 6ZMO|1|L5+6ZMO|1|L8, 7BHP|1|L5+7BHP|1|L8, 7F5S|1|L5+7F5S|1|L8, 7OW7|1|A+7OW7|1|C, 7QVP|1|L5+7QVP|1|L8, 7QVP|1|L6+7QVP|1|L1, 7XNX|1|L1+7XNX|1|L3, 7XNY|1|L1+7XNY|1|L3, 7ZFW|1|L5, 8A3D|1|A+8A3D|1|C, 8FKP|1|L3+8FKP|1|L1, 8FKQ|1|L3+8FKQ|1|L1, 8FKR|1|L3+8FKR|1|L1, 8FKS|1|L3+8FKS|1|L1, 8FKT|1|L3+8FKT|1|L1, 8FKU|1|L3+8FKU|1|L1, 8FKV|1|L3+8FKV|1|L1, 8FKW|1|L3+8FKW|1|L1, 8FKX|1|L3+8FKX|1|L1, 8FKY|1|L3+8FKY|1|L1, 8FKZ|1|L3+8FKZ|1|L1, 8FL0|1|L3, 8FL2|1|L3+8FL2|1|L1, 8FL3|1|L3+8FL3|1|L1, 8FL4|1|L3+8FL4|1|L1, 8FL6|1|L3+8FL6|1|L1, 8FL7|1|L3+8FL7|1|L1, 8FL9|1|L3+8FL9|1|L1, 8FLA|1|L3+8FLA|1|L1, 8FLB|1|L3+8FLB|1|L1, 8FLC|1|L3+8FLC|1|L1, 8FLD|1|L3+8FLD|1|L1, 8FLE|1|L3+8FLE|1|L1, 8FLF|1|L3+8FLF|1|L1, 8G5Y|1|L5+8G5Y|1|L8, 8G5Z|1|L5+8G5Z|1|L8, 8G60|1|L5+8G60|1|L8, 8G61|1|L5+8G61|1|L8, 8G6J|1|L5+8G6J|1|L8, 8GLP|1|L5+8GLP|1|L8, 8IDT|1|2+8IDT|1|8, 8IDY|1|2+8IDY|1|8, 8IE3|1|2+8IE3|1|8, 8INE|1|2+8INE|1|8, 8INF|1|2+8INF|1|8, 8INK|1|2+8INK|1|8, 8IPD|1|2+8IPD|1|8, 8IPX|1|2+8IPX|1|8, 8IPY|1|2+8IPY|1|8, 8IR1|1|2+8IR1|1|8, 8IR3|1|2+8IR3|1|8(1) 8BF9|1|5(0)

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
15A8L|1|AHuman eRF1 and the hCMV nascent peptide in the translation termination complexELECTRON MICROSCOPY3.8253
26LQM|1|2+ 6LQM|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state CELECTRON MICROSCOPY3.093433
36LSR|1|2+ 6LSR|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state BELECTRON MICROSCOPY3.133384
45LKS|1|L5+ 5LKS|1|L8Structure-function insights reveal the human ribosome as a cancer target for antibioticsELECTRON MICROSCOPY3.63776
55T2C|1|A+ 5T2C|1|CCryoEM structure of the human ribosome at 3.6 Angstrom resolutionELECTRON MICROSCOPY3.63776
64UG0|1|L5+ 4UG0|1|L8STRUCTURE OF THE HUMAN 80S RIBOSOMEELECTRON MICROSCOPY3.63776
74V6X|1|A5+ 4V6X|1|A8Structure of the human 80S ribosomeELECTRON MICROSCOPY54298
85AJ0|1|A2+ 5AJ0|1|A3Cryo electron microscopy of actively translating human polysomes (POST state).ELECTRON MICROSCOPY3.53612
96OLG|1|A2+ 6OLG|1|A3Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)ELECTRON MICROSCOPY3.43612
106OLZ|1|A2+ 6OLZ|1|A3Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAELECTRON MICROSCOPY3.93643
116OM0|1|t+ 6OM0|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
126OLE|1|t+ 6OLE|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
136OLI|1|t+ 6OLI|1|DStructure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)ELECTRON MICROSCOPY3.53607
146OLF|1|t+ 6OLF|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsELECTRON MICROSCOPY3.93607
156OM7|1|t+ 6OM7|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsELECTRON MICROSCOPY3.73607
166W6L|1|t+ 6W6L|1|DCryo-EM structure of the human ribosome-TMCO1 transloconELECTRON MICROSCOPY3.843510
178G6J|1|L5+ 8G6J|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)ELECTRON MICROSCOPY2.83559
188G5Z|1|L5+ 8G5Z|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)ELECTRON MICROSCOPY2.643560
198G61|1|L5+ 8G61|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)ELECTRON MICROSCOPY2.943528
208G5Y|1|L5+ 8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293594
218GLP|1|L5+ 8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673418
228G60|1|L5+ 8G60|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)ELECTRON MICROSCOPY2.543509
238A3D|1|A+ 8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673190
247OW7|1|A+ 7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23190
257BHP|1|L5+ 7BHP|1|L8Cryo-EM structure of the human Ebp1 - 80S ribosomeELECTRON MICROSCOPY3.33644
266Y0G|1|L5+ 6Y0G|1|L8Structure of human ribosome in classical-PRE stateELECTRON MICROSCOPY3.23644
276Y2L|1|L5+ 6Y2L|1|L8Structure of human ribosome in POST stateELECTRON MICROSCOPY33613
287QVP|1|L5+ 7QVP|1|L8Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33611
296QZP|1|L5+ 6QZP|1|L8High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93696
306Y57|1|L5+ 6Y57|1|L8Structure of human ribosome in hybrid-PRE stateELECTRON MICROSCOPY3.53574
317QVP|1|L6+ 7QVP|1|L1Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33572
326ZME|1|L5+ 6ZME|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33773
336ZMO|1|L5+ 6ZMO|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexELECTRON MICROSCOPY3.13773
346ZMI|1|L5+ 6ZMI|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63773
356Z6M|1|L5+ 6Z6M|1|L8Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1ELECTRON MICROSCOPY3.13772
366Y6X|1|L5+ 6Y6X|1|L8Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83773
376Z6N|1|L5+ 6Z6N|1|L8Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93772
386Z6L|1|L5+ 6Z6L|1|L8Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33772
396ZM7|1|L5+ 6ZM7|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73773
407XNX|1|L1+ 7XNX|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsELECTRON MICROSCOPY2.73686
417XNY|1|L1+ 7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53686
426IP8|1|1A+ 6IP8|1|1CCryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)ELECTRON MICROSCOPY3.93667
436LU8|1|2+ 6LU8|1|8Cryo-EM structure of a human pre-60S ribosomal subunit - state AELECTRON MICROSCOPY3.133386
446LSS|1|2+ 6LSS|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state preAELECTRON MICROSCOPY3.233383
458IDT|1|2+ 8IDT|1|8human nuclear pre-60S ribosomal particle - State GELECTRON MICROSCOPY2.83445
468IDY|1|2+ 8IDY|1|8human nuclear pre-60S ribosomal particle - State FELECTRON MICROSCOPY33564
478IE3|1|2+ 8IE3|1|8human nuclear pre-60S ribosomal particle - State EELECTRON MICROSCOPY3.33449
488FLC|1|L3+ 8FLC|1|L1Human nuclear pre-60S ribosomal subunit (State K3)ELECTRON MICROSCOPY2.763269
498FL9|1|L3+ 8FL9|1|L1Human nuclear pre-60S ribosomal subunit (State J3)ELECTRON MICROSCOPY2.753258
508FLF|1|L3+ 8FLF|1|L1Human nuclear pre-60S ribosomal subunit (State L3)ELECTRON MICROSCOPY2.653219
518FLE|1|L3+ 8FLE|1|L1Human nuclear pre-60S ribosomal subunit (State L2)ELECTRON MICROSCOPY2.483266
528FLD|1|L3+ 8FLD|1|L1Human nuclear pre-60S ribosomal subunit (State L1)ELECTRON MICROSCOPY2.583266
538FL6|1|L3+ 8FL6|1|L1Human nuclear pre-60S ribosomal subunit (State J1)ELECTRON MICROSCOPY2.623302
548FL7|1|L3+ 8FL7|1|L1Human nuclear pre-60S ribosomal subunit (State J2)ELECTRON MICROSCOPY2.553306
558FLB|1|L3+ 8FLB|1|L1Human nuclear pre-60S ribosomal subunit (State K2)ELECTRON MICROSCOPY2.553316
568FLA|1|L3+ 8FLA|1|L1Human nuclear pre-60S ribosomal subunit (State K1)ELECTRON MICROSCOPY2.633316
578INE|1|2+ 8INE|1|8human nuclear pre-60S ribosomal particle - State G'ELECTRON MICROSCOPY3.23461
588INF|1|2+ 8INF|1|8human nuclear pre-60S ribosomal particle - State F'ELECTRON MICROSCOPY33579
598IPD|1|2+ 8IPD|1|8human nuclear pre-60S ribosomal particle - State CELECTRON MICROSCOPY3.23418
608INK|1|2+ 8INK|1|8human nuclear pre-60S ribosomal particle - State DELECTRON MICROSCOPY3.23428
618IPY|1|2+ 8IPY|1|8human nuclear pre-60S ribosomal particle - State D'ELECTRON MICROSCOPY3.23419
628IPX|1|2+ 8IPX|1|8human nuclear pre-60S ribosomal particle - State C'ELECTRON MICROSCOPY4.33409
638FL4|1|L3+ 8FL4|1|L1Human nuclear pre-60S ribosomal subunit (State I3)ELECTRON MICROSCOPY2.893361
648FL3|1|L3+ 8FL3|1|L1Human nuclear pre-60S ribosomal subunit (State I2)ELECTRON MICROSCOPY2.533369
658FL2|1|L3+ 8FL2|1|L1Human nuclear pre-60S ribosomal subunit (State I1)ELECTRON MICROSCOPY2.673370
668FKZ|1|L3+ 8FKZ|1|L1Human nucleolar pre-60S ribosomal subunit (State G)ELECTRON MICROSCOPY3.042833
678IR1|1|2+ 8IR1|1|8human nuclear pre-60S ribosomal particle - State AELECTRON MICROSCOPY3.33308
688IR3|1|2+ 8IR3|1|8human nuclear pre-60S ribosomal particle - State B'ELECTRON MICROSCOPY3.53477
697F5S|1|L5+ 7F5S|1|L8human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723575
706XA1|1|L5+ 6XA1|1|L8Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83390
716IP6|1|1A+ 6IP6|1|1CCryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)ELECTRON MICROSCOPY4.53667
726IP5|1|1A+ 6IP5|1|1CCryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)ELECTRON MICROSCOPY3.93717
736SXO|1|L5Cryo-EM structure of the human Ebp1-ribosome complexELECTRON MICROSCOPY3.3268
747ZFW|1|L5Structure of human 80S ribosome obtained from ssDNA coated gridELECTRON MICROSCOPY3.8612
758FL0|1|L3Human nucleolar pre-60S ribosomal subunit (State H)ELECTRON MICROSCOPY2.911558
768FKU|1|L3+ 8FKU|1|L1Human nucleolar pre-60S ribosomal subunit (State C2)ELECTRON MICROSCOPY2.822185
778FKY|1|L3+ 8FKY|1|L1Human nucleolar pre-60S ribosomal subunit (State F)ELECTRON MICROSCOPY2.672585
788FKX|1|L3+ 8FKX|1|L1Human nucleolar pre-60S ribosomal subunit (State E)ELECTRON MICROSCOPY2.592250
798FKW|1|L3+ 8FKW|1|L1Human nucleolar pre-60S ribosomal subunit (State D2)ELECTRON MICROSCOPY2.52277
808FKV|1|L3+ 8FKV|1|L1Human nucleolar pre-60S ribosomal subunit (State D1)ELECTRON MICROSCOPY2.472213
818FKT|1|L3+ 8FKT|1|L1Human nucleolar pre-60S ribosomal subunit (State C1)ELECTRON MICROSCOPY2.812125
828FKS|1|L3+ 8FKS|1|L1Human nucleolar pre-60S ribosomal subunit (State B2)ELECTRON MICROSCOPY2.881824
838FKQ|1|L3+ 8FKQ|1|L1Human nucleolar pre-60S ribosomal subunit (State A2)ELECTRON MICROSCOPY2.761565
848FKR|1|L3+ 8FKR|1|L1Human nucleolar pre-60S ribosomal subunit (State B1)ELECTRON MICROSCOPY2.891767
858FKP|1|L3+ 8FKP|1|L1Human nucleolar pre-60S ribosomal subunit (State A1)ELECTRON MICROSCOPY2.851507
868BF9|1|5Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.ELECTRON MICROSCOPY2.691766

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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