#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.672023-04-19
28A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.672023-03-08
38G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.292023-04-19
48JDK|1|DLarge subunit ribosomal RNA28S ribosomal RNAHomo sapiensEukaryaRF02543Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)Electron microscopy2.262023-12-06
57XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.52023-04-05
66ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.62020-08-19
78IFE|1|1A+ 8IFE|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Arbekacin-added human 80S ribosomeElectron microscopy2.572024-02-14
88IFD|1|1A+ 8IFD|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Dibekacin-added human 80S ribosomeElectron microscopy2.592024-02-14
97OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.22022-10-05
108QFD|1|5+ 8QFD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002UFL1 E3 ligase bound 60S ribosomeElectron microscopy2.22024-02-21
118JDL|1|DLarge subunit ribosomal RNA28S ribosomal RNAHomo sapiensEukaryaRF02543Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)Electron microscopy2.422023-12-06
126ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.72020-07-29
138G60|1|L5+ 8G60|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)Electron microscopy2.542023-04-19
147XNX|1|L1+ 7XNX|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsElectron microscopy2.72023-04-05
158JDJ|1|DLarge subunit ribosomal RNA28S ribosomal RNAHomo sapiensEukaryaRF02543Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)Electron microscopy2.52023-12-06
168G5Z|1|L5+ 8G5Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)Electron microscopy2.642023-04-19
177F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.722022-06-22
188FL3|1|L3+ 8FL3|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I2)Electron microscopy2.532023-07-12
196Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.82020-07-08
206Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.92020-07-29
218FLE|1|L3+ 8FLE|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L2)Electron microscopy2.482023-07-12
228FLB|1|L3+ 8FLB|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K2)Electron microscopy2.552023-07-12
238JDM|1|DLarge subunit ribosomal RNA28S ribosomal RNAHomo sapiensEukaryaRF02543Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)Electron microscopy2.672023-12-06
248FL7|1|L3+ 8FL7|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J2)Electron microscopy2.552023-07-12
258G6J|1|L5+ 8G6J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)Electron microscopy2.82023-04-19
266QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.92019-04-24
276ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy32020-08-12
286Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy32020-07-29
297QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
308FLD|1|L3+ 8FLD|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L1)Electron microscopy2.582023-07-12
318FL6|1|L3+ 8FL6|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J1)Electron microscopy2.622023-07-12
328FLA|1|L3+ 8FLA|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K1)Electron microscopy2.632023-07-12
338FL2|1|L3+ 8FL2|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I1)Electron microscopy2.672023-07-12
347QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
358IDT|1|2+ 8IDT|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State GElectron microscopy2.82023-08-09
366XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.82020-10-07
376ZMO|1|L5+ 6ZMO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexElectron microscopy3.12020-08-19
386Z6M|1|L5+ 6Z6M|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1Electron microscopy3.12020-07-29
398FLF|1|L3+ 8FLF|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L3)Electron microscopy2.652023-07-12
408G61|1|L5+ 8G61|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)Electron microscopy2.942023-04-19
418OJ5|1|5+ 8OJ5|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution)Electron microscopy2.92024-02-21
428INF|1|2+ 8INF|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State F'Electron microscopy32023-08-09
438IDY|1|2+ 8IDY|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State FElectron microscopy32023-08-09
448FL9|1|L3+ 8FL9|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J3)Electron microscopy2.752023-07-12
458FLC|1|L3+ 8FLC|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K3)Electron microscopy2.762023-07-12
466OLE|1|t+ 6OLE|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
476OM0|1|t+ 6OM0|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
486Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy32020-04-15
498FL4|1|L3+ 8FL4|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I3)Electron microscopy2.892023-07-12
508OHD|1|5+ 8OHD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native)Electron microscopy3.12024-02-21
516LQM|1|2+ 6LQM|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state CElectron microscopy3.092020-08-26
526Y0G|1|L5+ 6Y0G|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in classical-PRE stateElectron microscopy3.22020-04-15
538Y0X|1|L5Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Dormant ribosome with SERBP1Electron microscopy3.32024-02-07
547BHP|1|L5+ 7BHP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human Ebp1 - 80S ribosomeElectron microscopy3.32021-02-03
556LU8|1|2+ 6LU8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a human pre-60S ribosomal subunit - state AElectron microscopy3.132020-08-26
566LSR|1|2+ 6LSR|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state BElectron microscopy3.132020-08-26
578INE|1|2+ 8INE|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State G'Electron microscopy3.22023-08-09
588INK|1|2+ 8INK|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State DElectron microscopy3.22023-08-09
598IPY|1|2+ 8IPY|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State D'Electron microscopy3.22023-08-09
608IPD|1|2+ 8IPD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State CElectron microscopy3.22023-08-09
618Y0W|1|L5Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543dormant ribosome with eIF5A, eEF2 and SERBP1Electron microscopy3.42024-02-07
628OJ8|1|5+ 8OJ8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native)Electron microscopy3.32024-02-21
636LSS|1|2+ 6LSS|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state preAElectron microscopy3.232020-08-26
648OJ0|1|5+ 8OJ0|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native)Electron microscopy3.32024-02-21
658IE3|1|2+ 8IE3|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State EElectron microscopy3.32023-08-09
668FKY|1|L3+ 8FKY|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State F)Electron microscopy2.672023-07-12
676OLI|1|t+ 6OLI|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)Electron microscopy3.52019-06-19
686OLG|1|A2+ 6OLG|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)Electron microscopy3.42019-06-19
698FKW|1|L3+ 8FKW|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D2)Electron microscopy2.52023-07-12
708IR1|1|2+ 8IR1|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRMAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State AElectron microscopy3.32023-08-09
718FKV|1|L3+ 8FKV|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D1)Electron microscopy2.472023-07-12
728IR3|1|2+ 8IR3|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State B'Electron microscopy3.52023-08-09
736Y57|1|L5+ 6Y57|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in hybrid-PRE stateElectron microscopy3.52020-04-15
748FKX|1|L3+ 8FKX|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State E)Electron microscopy2.592023-07-12
755T2C|1|A+ 5T2C|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CryoEM structure of the human ribosome at 3.6 Angstrom resolutionElectron microscopy3.62017-01-25
768FKZ|1|L3+ 8FKZ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State G)Electron microscopy3.042023-07-12
776OM7|1|t+ 6OM7|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsElectron microscopy3.72019-06-19
784UG0|1|L5+ 4UG0|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002STRUCTURE OF THE HUMAN 80S RIBOSOMEElectron microscopy3.62015-06-10
796OLF|1|t+ 6OLF|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsElectron microscopy3.92019-06-19
806W6L|1|t+ 6W6L|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human ribosome-TMCO1 transloconElectron microscopy3.842020-09-02
818FKU|1|L3+ 8FKU|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C2)Electron microscopy2.822023-07-12
828FKT|1|L3+ 8FKT|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C1)Electron microscopy2.812023-07-12
836IP5|1|1A+ 6IP5|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)Electron microscopy3.92019-05-29
846IP8|1|1A+ 6IP8|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)Electron microscopy3.92019-05-29
856OLZ|1|A2+ 6OLZ|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAElectron microscopy3.92019-06-19
868BF9|1|5Large subunit ribosomal RNARNA (1766)Ovis ariesEukaryaRF02543Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.Electron microscopy2.692023-11-01
875AJ0|1|A2+ 5AJ0|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo electron microscopy of actively translating human polysomes (POST state).Electron microscopy3.52015-05-20
888FKS|1|L3+ 8FKS|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B2)Electron microscopy2.882023-07-12
898FKR|1|L3+ 8FKR|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B1)Electron microscopy2.892023-07-12
908FKQ|1|L3+ 8FKQ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A2)Electron microscopy2.762023-07-12
918FKP|1|L3+ 8FKP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A1)Electron microscopy2.852023-07-12
928IPX|1|2+ 8IPX|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State C'Electron microscopy4.32023-08-09
938FL0|1|L3Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human nucleolar pre-60S ribosomal subunit (State H)Electron microscopy2.912023-07-12
945LKS|1|L5+ 5LKS|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure-function insights reveal the human ribosome as a cancer target for antibioticsElectron microscopy3.62017-04-26
956IP6|1|1A+ 6IP6|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)Electron microscopy4.52019-05-29
964V6X|1|A5+ 4V6X|1|A8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the human 80S ribosomeElectron microscopy52014-07-09
978ONY|1|5Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human Methionine Aminopeptidase 2 at the 80S ribosomeElectron microscopy2.922024-02-21
986SXO|1|L5Large subunit ribosomal RNA28S ribosomal RNA including ES27L-B (2839-3265)Homo sapiensEukaryaRF02543Cryo-EM structure of the human Ebp1-ribosome complexElectron microscopy3.32020-02-19
997ZFW|1|L5Large subunit ribosomal RNARNA (615-MER)Homo sapiensEukaryaRF02543Structure of human 80S ribosome obtained from ssDNA coated gridElectron microscopy3.82022-11-23
1005A8L|1|ALarge subunit ribosomal RNA28S RIBOSOMAL RNAHomo sapiensEukaryaRF02543Human eRF1 and the hCMV nascent peptide in the translation termination complexElectron microscopy3.82015-12-02

Release history

Release3.3233.3243.3253.3263.3273.3283.3293.3303.3313.332
Date2024-02-212024-02-282024-03-062024-03-132024-03-202024-03-272024-04-032024-04-102024-04-172024-04-24

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
15A8L|1|AHuman eRF1 and the hCMV nascent peptide in the translation termination complexELECTRON MICROSCOPY3.8253
26ZMI|1|L5+ 6ZMI|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63773
38IR1|1|2+ 8IR1|1|8human nuclear pre-60S ribosomal particle - State AELECTRON MICROSCOPY3.33308
48IR3|1|2+ 8IR3|1|8human nuclear pre-60S ribosomal particle - State B'ELECTRON MICROSCOPY3.53477
58FKZ|1|L3+ 8FKZ|1|L1Human nucleolar pre-60S ribosomal subunit (State G)ELECTRON MICROSCOPY3.042833
68FL2|1|L3+ 8FL2|1|L1Human nuclear pre-60S ribosomal subunit (State I1)ELECTRON MICROSCOPY2.673370
78FL3|1|L3+ 8FL3|1|L1Human nuclear pre-60S ribosomal subunit (State I2)ELECTRON MICROSCOPY2.533369
88FL4|1|L3+ 8FL4|1|L1Human nuclear pre-60S ribosomal subunit (State I3)ELECTRON MICROSCOPY2.893361
98IPX|1|2+ 8IPX|1|8human nuclear pre-60S ribosomal particle - State C'ELECTRON MICROSCOPY4.33409
108IPY|1|2+ 8IPY|1|8human nuclear pre-60S ribosomal particle - State D'ELECTRON MICROSCOPY3.23419
118INK|1|2+ 8INK|1|8human nuclear pre-60S ribosomal particle - State DELECTRON MICROSCOPY3.23428
128IPD|1|2+ 8IPD|1|8human nuclear pre-60S ribosomal particle - State CELECTRON MICROSCOPY3.23418
138IE3|1|2+ 8IE3|1|8human nuclear pre-60S ribosomal particle - State EELECTRON MICROSCOPY3.33449
148IDY|1|2+ 8IDY|1|8human nuclear pre-60S ribosomal particle - State FELECTRON MICROSCOPY33564
158IDT|1|2+ 8IDT|1|8human nuclear pre-60S ribosomal particle - State GELECTRON MICROSCOPY2.83445
166LSS|1|2+ 6LSS|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state preAELECTRON MICROSCOPY3.233383
176LU8|1|2+ 6LU8|1|8Cryo-EM structure of a human pre-60S ribosomal subunit - state AELECTRON MICROSCOPY3.133386
188INE|1|2+ 8INE|1|8human nuclear pre-60S ribosomal particle - State G'ELECTRON MICROSCOPY3.23461
198INF|1|2+ 8INF|1|8human nuclear pre-60S ribosomal particle - State F'ELECTRON MICROSCOPY33579
208FLC|1|L3+ 8FLC|1|L1Human nuclear pre-60S ribosomal subunit (State K3)ELECTRON MICROSCOPY2.763269
218FL9|1|L3+ 8FL9|1|L1Human nuclear pre-60S ribosomal subunit (State J3)ELECTRON MICROSCOPY2.753258
228FLA|1|L3+ 8FLA|1|L1Human nuclear pre-60S ribosomal subunit (State K1)ELECTRON MICROSCOPY2.633316
238FLB|1|L3+ 8FLB|1|L1Human nuclear pre-60S ribosomal subunit (State K2)ELECTRON MICROSCOPY2.553316
248FL6|1|L3+ 8FL6|1|L1Human nuclear pre-60S ribosomal subunit (State J1)ELECTRON MICROSCOPY2.623302
258FL7|1|L3+ 8FL7|1|L1Human nuclear pre-60S ribosomal subunit (State J2)ELECTRON MICROSCOPY2.553306
268FLE|1|L3+ 8FLE|1|L1Human nuclear pre-60S ribosomal subunit (State L2)ELECTRON MICROSCOPY2.483266
278FLD|1|L3+ 8FLD|1|L1Human nuclear pre-60S ribosomal subunit (State L1)ELECTRON MICROSCOPY2.583266
288FLF|1|L3+ 8FLF|1|L1Human nuclear pre-60S ribosomal subunit (State L3)ELECTRON MICROSCOPY2.653219
296LQM|1|2+ 6LQM|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state CELECTRON MICROSCOPY3.093433
308IFD|1|1A+ 8IFD|1|1CDibekacin-added human 80S ribosomeELECTRON MICROSCOPY2.593717
318IFE|1|1A+ 8IFE|1|1CArbekacin-added human 80S ribosomeELECTRON MICROSCOPY2.573717
326IP5|1|1A+ 6IP5|1|1CCryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)ELECTRON MICROSCOPY3.93717
336IP6|1|1A+ 6IP6|1|1CCryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)ELECTRON MICROSCOPY4.53667
346IP8|1|1A+ 6IP8|1|1CCryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)ELECTRON MICROSCOPY3.93667
358JDM|1|DStructure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)ELECTRON MICROSCOPY2.673399
368JDK|1|DStructure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)ELECTRON MICROSCOPY2.263399
378JDJ|1|DStructure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)ELECTRON MICROSCOPY2.53399
388JDL|1|DStructure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)ELECTRON MICROSCOPY2.423399
397BHP|1|L5+ 7BHP|1|L8Cryo-EM structure of the human Ebp1 - 80S ribosomeELECTRON MICROSCOPY3.33644
406Z6L|1|L5+ 6Z6L|1|L8Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33772
416Z6N|1|L5+ 6Z6N|1|L8Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93772
426Y6X|1|L5+ 6Y6X|1|L8Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83773
436Z6M|1|L5+ 6Z6M|1|L8Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1ELECTRON MICROSCOPY3.13772
448Y0X|1|L5Dormant ribosome with SERBP1ELECTRON MICROSCOPY3.33658
458Y0W|1|L5dormant ribosome with eIF5A, eEF2 and SERBP1ELECTRON MICROSCOPY3.43666
466ZMO|1|L5+ 6ZMO|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexELECTRON MICROSCOPY3.13773
476ZME|1|L5+ 6ZME|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33773
486ZM7|1|L5+ 6ZM7|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73773
497XNY|1|L1+ 7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53686
507XNX|1|L1+ 7XNX|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsELECTRON MICROSCOPY2.73686
517QVP|1|L6+ 7QVP|1|L1Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33572
526Y57|1|L5+ 6Y57|1|L8Structure of human ribosome in hybrid-PRE stateELECTRON MICROSCOPY3.53574
536Y0G|1|L5+ 6Y0G|1|L8Structure of human ribosome in classical-PRE stateELECTRON MICROSCOPY3.23644
547QVP|1|L5+ 7QVP|1|L8Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33611
556Y2L|1|L5+ 6Y2L|1|L8Structure of human ribosome in POST stateELECTRON MICROSCOPY33613
566QZP|1|L5+ 6QZP|1|L8High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93696
577F5S|1|L5+ 7F5S|1|L8human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723575
586XA1|1|L5+ 6XA1|1|L8Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83390
598OJ5|1|5+ 8OJ5|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution)ELECTRON MICROSCOPY2.93474
608OHD|1|5+ 8OHD|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native)ELECTRON MICROSCOPY3.13474
618OJ0|1|5+ 8OJ0|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native)ELECTRON MICROSCOPY3.33474
628OJ8|1|5+ 8OJ8|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native)ELECTRON MICROSCOPY3.33515
638G60|1|L5+ 8G60|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)ELECTRON MICROSCOPY2.543509
648A3D|1|A+ 8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673190
657OW7|1|A+ 7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23190
668G5Z|1|L5+ 8G5Z|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)ELECTRON MICROSCOPY2.643560
678G6J|1|L5+ 8G6J|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)ELECTRON MICROSCOPY2.83559
688G61|1|L5+ 8G61|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)ELECTRON MICROSCOPY2.943528
698GLP|1|L5+ 8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673418
708G5Y|1|L5+ 8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293594
716W6L|1|t+ 6W6L|1|DCryo-EM structure of the human ribosome-TMCO1 transloconELECTRON MICROSCOPY3.843510
726OM7|1|t+ 6OM7|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsELECTRON MICROSCOPY3.73607
736OLF|1|t+ 6OLF|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsELECTRON MICROSCOPY3.93607
746OLI|1|t+ 6OLI|1|DStructure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)ELECTRON MICROSCOPY3.53607
756OLE|1|t+ 6OLE|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
766OM0|1|t+ 6OM0|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
776OLZ|1|A2+ 6OLZ|1|A3Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAELECTRON MICROSCOPY3.93643
786OLG|1|A2+ 6OLG|1|A3Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)ELECTRON MICROSCOPY3.43612
795AJ0|1|A2+ 5AJ0|1|A3Cryo electron microscopy of actively translating human polysomes (POST state).ELECTRON MICROSCOPY3.53612
804V6X|1|A5+ 4V6X|1|A8Structure of the human 80S ribosomeELECTRON MICROSCOPY54298
814UG0|1|L5+ 4UG0|1|L8STRUCTURE OF THE HUMAN 80S RIBOSOMEELECTRON MICROSCOPY3.63776
825T2C|1|A+ 5T2C|1|CCryoEM structure of the human ribosome at 3.6 Angstrom resolutionELECTRON MICROSCOPY3.63776
835LKS|1|L5+ 5LKS|1|L8Structure-function insights reveal the human ribosome as a cancer target for antibioticsELECTRON MICROSCOPY3.63776
848QFD|1|5+ 8QFD|1|8UFL1 E3 ligase bound 60S ribosomeELECTRON MICROSCOPY2.23130
856LSR|1|2+ 6LSR|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state BELECTRON MICROSCOPY3.133384
866SXO|1|L5Cryo-EM structure of the human Ebp1-ribosome complexELECTRON MICROSCOPY3.3268
878ONY|1|5Human Methionine Aminopeptidase 2 at the 80S ribosomeELECTRON MICROSCOPY2.92156
887ZFW|1|L5Structure of human 80S ribosome obtained from ssDNA coated gridELECTRON MICROSCOPY3.8612
898FL0|1|L3Human nucleolar pre-60S ribosomal subunit (State H)ELECTRON MICROSCOPY2.911558
908FKT|1|L3+ 8FKT|1|L1Human nucleolar pre-60S ribosomal subunit (State C1)ELECTRON MICROSCOPY2.812125
918FKV|1|L3+ 8FKV|1|L1Human nucleolar pre-60S ribosomal subunit (State D1)ELECTRON MICROSCOPY2.472213
928FKW|1|L3+ 8FKW|1|L1Human nucleolar pre-60S ribosomal subunit (State D2)ELECTRON MICROSCOPY2.52277
938FKU|1|L3+ 8FKU|1|L1Human nucleolar pre-60S ribosomal subunit (State C2)ELECTRON MICROSCOPY2.822185
948FKX|1|L3+ 8FKX|1|L1Human nucleolar pre-60S ribosomal subunit (State E)ELECTRON MICROSCOPY2.592250
958FKY|1|L3+ 8FKY|1|L1Human nucleolar pre-60S ribosomal subunit (State F)ELECTRON MICROSCOPY2.672585
968FKR|1|L3+ 8FKR|1|L1Human nucleolar pre-60S ribosomal subunit (State B1)ELECTRON MICROSCOPY2.891767
978FKP|1|L3+ 8FKP|1|L1Human nucleolar pre-60S ribosomal subunit (State A1)ELECTRON MICROSCOPY2.851507
988FKS|1|L3+ 8FKS|1|L1Human nucleolar pre-60S ribosomal subunit (State B2)ELECTRON MICROSCOPY2.881824
998FKQ|1|L3+ 8FKQ|1|L1Human nucleolar pre-60S ribosomal subunit (State A2)ELECTRON MICROSCOPY2.761565
1008BF9|1|5Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.ELECTRON MICROSCOPY2.691766

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


Coloring options:

Copyright 2024 BGSU RNA group. Page generated in 0.0132 s