#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. Å#NTsDate
18H6L|1|5A (rep)U5 spliceosomal RNApre-mRNA, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the early B state.Electron microscopy2.61152024-05-01
28H6K|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the mature B state.Electron microscopy2.71152024-05-01
38C6J|1|5U5 spliceosomal RNAPM5 5' Exon, U5 snRNAHomo sapiensEukaryaRF00020Human spliceosomal PM5 C* complexElectron microscopy2.81132023-07-12
46QW6|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.Electron microscopy2.921042019-04-17
57DVQ|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)Electron microscopy2.89902021-03-31
67QTT|1|eU5 spliceosomal RNAMINX, U5 snRNAHomo sapiensEukaryaRF00020Structural organization of a late activated human spliceosome (Baqr, core region)Electron microscopy3.1982023-05-10
78Q7N|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)Electron microscopy3.11152024-01-24
88H6E|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.Electron microscopy3.21142024-05-01
98H6J|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.Electron microscopy3.251142024-05-01
108Q7Q|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2)Electron microscopy3.21042024-04-17
118Q91|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human 20S U5 snRNP coreElectron microscopy3.11042024-03-27
126QX9|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).Electron microscopy3.281042019-04-17
138RC0|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human 20S U5 snRNPElectron microscopy3.21042024-03-27
146QDV|1|5U5 spliceosomal RNALigated exons: MINX mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human post-catalytic P complex spliceosomeElectron microscopy3.3752019-02-20
156ZYM|1|5U5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human C Complex Spliceosome - High-resolution COREElectron microscopy3.4742020-10-14
168Y6O|1|BU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP partElectron microscopy3.381092024-03-20
176ICZ|1|BU5 spliceosomal RNApre-mRNA, U5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromElectron microscopy3972019-03-13
187W59|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020The cryo-EM structure of human pre-C*-I complexElectron microscopy3.6842022-06-22
197W5A|1|BU5 spliceosomal RNAPre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020The cryo-EM structure of human pre-C*-II complexElectron microscopy3.6842022-06-22
206FF4|1|5U5 spliceosomal RNApre mRNA, U2 snRNA, U5 snRNAHomo sapiensEukaryaRF00020human Bact spliceosome core structureElectron microscopy3.4702018-08-29
218Q7V|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1)Electron microscopy3.81042024-04-17
226ID0|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionElectron microscopy2.9982019-03-13
235XJC|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstromElectron microscopy3.6842017-07-05
248Q7W|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3)Electron microscopy3.91042024-04-17
256ID1|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionElectron microscopy2.86982019-03-13
267W5B|1|BU5 spliceosomal RNAPre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020The cryo-EM structure of human C* complexElectron microscopy4.3842022-06-22
277AAV|1|5U5 spliceosomal RNAMINX M3 pre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human pre-Bact-2 spliceosome core structureElectron microscopy4.2692020-12-09
285YZG|1|BU5 spliceosomal RNAPre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolutionElectron microscopy4.1842018-08-08
296AHD|1|BU5 spliceosomal RNApre-mRNA, U5snRNAHomo sapiensEukaryaRF00020The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionElectron microscopy3.81152018-11-14
305O9Z|1|5U5 spliceosomal RNAHomo sapiens U5 A small nuclear RNA, MINX pre-mRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)Electron microscopy4.51142017-08-16
318Q7X|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4)Electron microscopy4.61042024-04-17
326FF7|1|5U5 spliceosomal RNApre-mRNA, U2 snRNA, U5 snRNAHomo sapiensEukaryaRF00020human Bact spliceosome core structureElectron microscopy4.5702019-03-13
337ABF|1|5U5 spliceosomal RNAMINX M3 RNA, U5 small nuclear RNAHomo sapiensEukaryaRF00020Human pre-Bact-1 spliceosome core structureElectron microscopy3.9582020-12-09
348QO9|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human spliceosomal B complex protomerElectron microscopy5.291152024-01-24
355Z58|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.Electron microscopy4.9842018-09-19
367A5P|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Human C Complex Spliceosome - Medium-resolution PERIPHERYElectron microscopy5402020-10-14
375Z56|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.Electron microscopy5.1842018-09-19
388CH6|1|eU5 spliceosomal RNAMINX-M3, RNU5A-1Homo sapiensEukaryaRF00020Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).Electron microscopy5.9982023-05-10
396AH0|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)Electron microscopy5.71152018-11-14
405MQF|1|5U5 spliceosomal RNAHomo sapiens U5 A small nuclear RNA, MINX pre-mRNA (intron)Homo sapiensEukaryaRF00020Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)Electron microscopy5.91142017-03-22
415Z57|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromElectron microscopy6.5842018-09-19
423JCR|1|HU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF000203D structure determination of the human*U4/U6.U5* tri-snRNP complexElectron microscopy7632016-03-09
437ABG|1|5U5 spliceosomal RNAMINX M3 pre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human pre-Bact-1 spliceosomeElectron microscopy7.81142020-12-23
447ABI|1|5U5 spliceosomal RNAMINX M3 pre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human pre-Bact-2 spliceosomeElectron microscopy81142021-02-10

Release history

Release3.3333.3343.335
Date2024-05-012024-05-082024-05-15

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolution#NTs
17A5P|1|5Human C Complex Spliceosome - Medium-resolution PERIPHERYELECTRON MICROSCOPY540
25MQF|1|5Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)ELECTRON MICROSCOPY5.9114
35O9Z|1|5Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)ELECTRON MICROSCOPY4.5114
46AH0|1|BThe Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)ELECTRON MICROSCOPY5.7115
56AHD|1|BThe Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionELECTRON MICROSCOPY3.8115
68H6L|1|5ACryo-EM structure of human exon-defined spliceosome in the early B state.ELECTRON MICROSCOPY2.6115
78H6K|1|5ACryo-EM structure of human exon-defined spliceosome in the mature B state.ELECTRON MICROSCOPY2.7115
88Q7N|1|5cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)ELECTRON MICROSCOPY3.1115
98QO9|1|5Cryo-EM structure of a human spliceosomal B complex protomerELECTRON MICROSCOPY5.29115
106ZYM|1|5Human C Complex Spliceosome - High-resolution COREELECTRON MICROSCOPY3.474
116FF7|1|5human Bact spliceosome core structureELECTRON MICROSCOPY4.570
126FF4|1|5human Bact spliceosome core structureELECTRON MICROSCOPY3.470
137AAV|1|5Human pre-Bact-2 spliceosome core structureELECTRON MICROSCOPY4.269
147ABI|1|5Human pre-Bact-2 spliceosomeELECTRON MICROSCOPY8114
157ABG|1|5Human pre-Bact-1 spliceosomeELECTRON MICROSCOPY7.8114
167ABF|1|5Human pre-Bact-1 spliceosome core structureELECTRON MICROSCOPY3.958
178H6E|1|5ACryo-EM structure of human exon-defined spliceosome in the late pre-B state.ELECTRON MICROSCOPY3.2114
188H6J|1|5ACryo-EM structure of human exon-defined spliceosome in the mature pre-B state.ELECTRON MICROSCOPY3.25114
198Y6O|1|BCryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP partELECTRON MICROSCOPY3.38109
208Q7V|1|5Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1)ELECTRON MICROSCOPY3.8104
218Q7Q|1|5Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2)ELECTRON MICROSCOPY3.2104
228Q7X|1|5Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4)ELECTRON MICROSCOPY4.6104
238Q7W|1|5Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3)ELECTRON MICROSCOPY3.9104
246QW6|1|5Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.ELECTRON MICROSCOPY2.92104
256QX9|1|5Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).ELECTRON MICROSCOPY3.28104
268Q91|1|5Structure of the human 20S U5 snRNP coreELECTRON MICROSCOPY3.1104
278RC0|1|5Structure of the human 20S U5 snRNPELECTRON MICROSCOPY3.2104
288C6J|1|5Human spliceosomal PM5 C* complexELECTRON MICROSCOPY2.8113
296QDV|1|5Human post-catalytic P complex spliceosomeELECTRON MICROSCOPY3.375
307DVQ|1|BCryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)ELECTRON MICROSCOPY2.8990
316ICZ|1|BCryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromELECTRON MICROSCOPY397
326ID0|1|BCryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.998
336ID1|1|BCryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.8698
347W59|1|BThe cryo-EM structure of human pre-C*-I complexELECTRON MICROSCOPY3.684
357W5A|1|BThe cryo-EM structure of human pre-C*-II complexELECTRON MICROSCOPY3.684
367W5B|1|BThe cryo-EM structure of human C* complexELECTRON MICROSCOPY4.384
377QTT|1|eStructural organization of a late activated human spliceosome (Baqr, core region)ELECTRON MICROSCOPY3.198
388CH6|1|eStructure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).ELECTRON MICROSCOPY5.998
395XJC|1|BCryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstromELECTRON MICROSCOPY3.684
405YZG|1|BThe Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolutionELECTRON MICROSCOPY4.184
415Z56|1|Bcryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.ELECTRON MICROSCOPY5.184
425Z57|1|BCryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromELECTRON MICROSCOPY6.584
435Z58|1|BCryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.ELECTRON MICROSCOPY4.984
443JCR|1|H3D structure determination of the human*U4/U6.U5* tri-snRNP complexELECTRON MICROSCOPY763

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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