#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. Å#NTsDate
16JDV|1|B+ 6JDV|1|C+ 6JDV|1|D (rep)non-target DNA strand, sgRNA, target DNA strandsynthetic constructCrystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic stateX-ray diffraction3.11892019-11-06
26JE4|1|F+ 6JE4|1|G+ 6JE4|1|Hnon-target DNA strand, sgRNA, target DNA strandsynthetic constructCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-ray diffraction3.071852019-11-06
36KC8|1|B+ 6KC8|1|C+ 6KC8|1|P+ 6KC8|1|DDNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*A)-3'), DNA (5'-D(P*AP*AP*GP*TP*TP*AP*AP*AP*TP*AP*GP*CP*AP*GP*AP*GP*TP*GP*AP*CP*C)-3'), sgRNAsynthetic constructCrystal structure of WT Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in post-cleavage stateX-ray diffraction2.91762019-11-06
46JE4|1|L+ 6JE4|1|M+ 6JE4|1|Nnon-target DNA strand, sgRNA, target DNA strandsynthetic constructCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-ray diffraction3.071862019-11-06
56JE4|1|P+ 6JE4|1|Q+ 6JE4|1|Rnon-target DNA strand, sgRNA, target DNA strandsynthetic constructCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-ray diffraction3.071832019-11-06
66JE3|1|B+ 6JE3|1|C+ 6JE3|1|Dnon-target DNA strand, sgRNA, target DNA strandsynthetic constructCrystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhangX-ray diffraction2.931652019-11-06
76JE4|1|B+ 6JE4|1|C+ 6JE4|1|Dnon-target DNA strand, sgRNA, target DNA strandsynthetic constructCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-ray diffraction3.071822019-11-06
86JFU|1|B+ 6JFU|1|C+ 6JFU|1|Dnon-target strand, sgRNA, target-strand DNAsynthetic constructCrystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM)X-ray diffraction3.21512019-11-06
96KC7|1|B+ 6KC7|1|C+ 6KC7|1|DDNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*AP*AP*AP*GP*TP*T)-3'), sgRNAsynthetic constructCrystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in seed-base paring stateX-ray diffraction3.31412019-11-06
106JE9|1|BsgRNAsynthetic constructCrystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-ray diffraction3.461152019-11-06
116JE9|1|DsgRNAsynthetic constructCrystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-ray diffraction3.461132019-11-06
126JDQ|1|BsgRNAsynthetic constructCrystal structure of Nme1Cas9 in complex with sgRNAX-ray diffraction2.951172019-11-06

Release history

Release3.3783.3793.3803.381
Date2025-03-132025-03-192025-03-262025-04-02

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolution#NTs
16JE4|1|F+ 6JE4|1|G+ 6JE4|1|HCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-RAY DIFFRACTION3.07185
26JE4|1|L+ 6JE4|1|M+ 6JE4|1|NCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-RAY DIFFRACTION3.07186
36JE4|1|B+ 6JE4|1|C+ 6JE4|1|DCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-RAY DIFFRACTION3.07182
46JE4|1|P+ 6JE4|1|Q+ 6JE4|1|RCrystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-RAY DIFFRACTION3.07183
56JE9|1|BCrystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-RAY DIFFRACTION3.46115
66JE9|1|DCrystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomersX-RAY DIFFRACTION3.46113
76JDQ|1|BCrystal structure of Nme1Cas9 in complex with sgRNAX-RAY DIFFRACTION2.95117
86KC7|1|B+ 6KC7|1|C+ 6KC7|1|DCrystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in seed-base paring stateX-RAY DIFFRACTION3.3141
96KC8|1|B+ 6KC8|1|C+ 6KC8|1|P+ 6KC8|1|DCrystal structure of WT Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in post-cleavage stateX-RAY DIFFRACTION2.9176
106JDV|1|B+ 6JDV|1|C+ 6JDV|1|DCrystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic stateX-RAY DIFFRACTION3.1189
116JE3|1|B+ 6JE3|1|C+ 6JE3|1|DCrystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhangX-RAY DIFFRACTION2.93165
126JFU|1|B+ 6JFU|1|C+ 6JFU|1|DCrystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM)X-RAY DIFFRACTION3.2151

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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