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Equivalence class NR_3.0_65061.19 Obsolete

#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.672023-04-19
28A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.672023-03-08
38G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.292023-04-19
47XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.52023-04-05
56ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.62020-08-19
67OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.22022-10-05
76ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.72020-07-29
88G60|1|L5+ 8G60|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)Electron microscopy2.542023-04-19
97XNX|1|L1+ 7XNX|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsElectron microscopy2.72023-04-05
108G5Z|1|L5+ 8G5Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)Electron microscopy2.642023-04-19
117F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.722022-06-22
126Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.82020-07-08
136Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.92020-07-29
148G6J|1|L5+ 8G6J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)Electron microscopy2.82023-04-19
156QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.92019-04-24
166ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy32020-08-12
176Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy32020-07-29
187QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
197QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
206XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.82020-10-07
218G61|1|L5+ 8G61|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)Electron microscopy2.942023-04-19
226Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy32020-04-15

Release history

Release3.2793.2803.2813.2823.2833.2843.2853.2863.2873.2883.2893.290
Date2023-04-192023-04-262023-05-032023-05-102023-05-172023-05-242023-05-312023-06-072023-06-142023-06-212023-06-282023-07-05

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_3.0_65061.19NR_3.0_65061.183.279(16) 7QVP|1|L5+7QVP|1|L8, 6QZP|1|L5+6QZP|1|L8, 6Z6N|1|L5+6Z6N|1|L8, 7OW7|1|A+7OW7|1|C, 8A3D|1|A+8A3D|1|C, 6Z6L|1|L5+6Z6L|1|L8, 7F5S|1|L5+7F5S|1|L8, 7XNY|1|L1+7XNY|1|L3, 6Y6X|1|L5+6Y6X|1|L8, 6ZMI|1|L5+6ZMI|1|L8, 7XNX|1|L1+7XNX|1|L3, 6Y2L|1|L5+6Y2L|1|L8, 6ZME|1|L5+6ZME|1|L8, 7QVP|1|L6+7QVP|1|L1, 6XA1|1|L5+6XA1|1|L8, 6ZM7|1|L5+6ZM7|1|L8(6) 8G5Y|1|L5+8G5Y|1|L8, 8G60|1|L5+8G60|1|L8, 8G6J|1|L5+8G6J|1|L8, 8GLP|1|L5+8GLP|1|L8, 8G5Z|1|L5+8G5Z|1|L8, 8G61|1|L5+8G61|1|L8(0)

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child
NR_3.0_65061.19NR_3.0_65061.203.291(22) 7QVP|1|L5+7QVP|1|L8, 8G61|1|L5+8G61|1|L8, 6QZP|1|L5+6QZP|1|L8, 6ZMI|1|L5+6ZMI|1|L8, 8A3D|1|A+8A3D|1|C, 6Z6L|1|L5+6Z6L|1|L8, 7QVP|1|L6+7QVP|1|L1, 8G6J|1|L5+8G6J|1|L8, 6XA1|1|L5+6XA1|1|L8, 8G5Y|1|L5+8G5Y|1|L8, 6Z6N|1|L5+6Z6N|1|L8, 7XNX|1|L1+7XNX|1|L3, 7F5S|1|L5+7F5S|1|L8, 8G5Z|1|L5+8G5Z|1|L8, 6ZM7|1|L5+6ZM7|1|L8, 8GLP|1|L5+8GLP|1|L8, 6Y2L|1|L5+6Y2L|1|L8, 7OW7|1|A+7OW7|1|C, 7XNY|1|L1+7XNY|1|L3, 6Y6X|1|L5+6Y6X|1|L8, 8G60|1|L5+8G60|1|L8, 6ZME|1|L5+6ZME|1|L8(0) (23) 8FL6|1|L3+8FL6|1|L1, 8FKW|1|L3+8FKW|1|L1, 8FL0|1|L3, 8FKS|1|L3+8FKS|1|L1, 8FLC|1|L3+8FLC|1|L1, 8FKP|1|L3+8FKP|1|L1, 8FL3|1|L3+8FL3|1|L1, 8FL9|1|L3+8FL9|1|L1, 8FKU|1|L3+8FKU|1|L1, 8FKY|1|L3+8FKY|1|L1, 8FLE|1|L3+8FLE|1|L1, 8FL4|1|L3+8FL4|1|L1, 8FKV|1|L3+8FKV|1|L1, 8FKR|1|L3+8FKR|1|L1, 8FLB|1|L3+8FLB|1|L1, 8FLF|1|L3+8FLF|1|L1, 8FL2|1|L3+8FL2|1|L1, 8FL7|1|L3+8FL7|1|L1, 8FKT|1|L3+8FKT|1|L1, 8FKX|1|L3+8FKX|1|L1, 8FLD|1|L3+8FLD|1|L1, 8FKQ|1|L3+8FKQ|1|L1, 8FLA|1|L3+8FLA|1|L1

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
17F5S|1|L5+7F5S|1|L8human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723575
26QZP|1|L5+6QZP|1|L8High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93696
36Y6X|1|L5+6Y6X|1|L8Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83773
46Z6N|1|L5+6Z6N|1|L8Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93772
56Z6L|1|L5+6Z6L|1|L8Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33772
66ZM7|1|L5+6ZM7|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73773
76ZMI|1|L5+6ZMI|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63773
86ZME|1|L5+6ZME|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33773
97XNY|1|L1+7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53686
107XNX|1|L1+7XNX|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsELECTRON MICROSCOPY2.73686
117QVP|1|L6+7QVP|1|L1Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33572
127QVP|1|L5+7QVP|1|L8Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33611
136Y2L|1|L5+6Y2L|1|L8Structure of human ribosome in POST stateELECTRON MICROSCOPY33613
146XA1|1|L5+6XA1|1|L8Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83390
157OW7|1|A+7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23190
168A3D|1|A+8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673190
178G60|1|L5+8G60|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)ELECTRON MICROSCOPY2.543509
188GLP|1|L5+8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673418
198G5Y|1|L5+8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293594
208G61|1|L5+8G61|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)ELECTRON MICROSCOPY2.943528
218G6J|1|L5+8G6J|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)ELECTRON MICROSCOPY2.83559
228G5Z|1|L5+8G5Z|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)ELECTRON MICROSCOPY2.643560
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