HL_10PX_116

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

UUGGGAAG

Length

8 nucleotides

Bulged bases

10PX|1|2A|A|311

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_10PX_116 not in the Motif Atlas

Homologous match to HL_7A0S_010

Geometric discrepancy: 0.1794

The information below is about HL_7A0S_010

Detailed Annotation

T-loop with 1 bulged base

Broad Annotation

T-loop

Motif group

HL_13999.4

Basepair signature

cWW-tWH-F-F-F

Number of instances in this motif group

24

Unit IDs

10PX|1|2A|U|305
10PX|1|2A|U|306
10PX|1|2A|G|307
10PX|1|2A|G|308
10PX|1|2A|G|309
10PX|1|2A|A|310
10PX|1|2A|A|311
10PX|1|2A|G|312

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 2Y

50S ribosomal protein L24