HL_10PX_118

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

GUGAAAGCC

Length

9 nucleotides

Bulged bases

10PX|1|2A|G|329, 10PX|1|2A|A|330, 10PX|1|2A|A|331

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_10PX_118 not in the Motif Atlas

Homologous match to HL_7A0S_012

Geometric discrepancy: 0.3463

The information below is about HL_7A0S_012

Detailed Annotation

T-loop with unstacked turn

Broad Annotation

T-loop

Motif group

HL_27670.5

Basepair signature

cWW-tWH-F-F

Number of instances in this motif group

17

Unit IDs

10PX|1|2A|G|327
10PX|1|2A|U|328
10PX|1|2A|G|329
10PX|1|2A|A|330
10PX|1|2A|A|331
10PX|1|2A|A|332
10PX|1|2A|G|333
10PX|1|2A|C|334
10PX|1|2A|C|335

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 2F

50S ribosomal protein L4

Chain 2Y

50S ribosomal protein L24