HL_3G6E_010

3D structure

PDB id

3G6E (explore in PDB, NAKB, or RNA 3D Hub)

Description

Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit

Experimental method

X-RAY DIFFRACTION

Resolution

2.7 Å

Loop

Sequence

UUGGAAUA

Length

8 nucleotides

Bulged bases

3G6E|1|0|U|318

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_3G6E_010 not in the Motif Atlas

Homologous match to HL_4V9F_010

Geometric discrepancy: 0.0459

The information below is about HL_4V9F_010

Detailed Annotation

T-loop with 2 stacked bulged bases

Broad Annotation

T-loop

Motif group

HL_01609.3

Basepair signature

cWW-tWH-F-F-F

Number of instances in this motif group

18

Unit IDs

3G6E|1|0|U|312
3G6E|1|0|U|313
3G6E|1|0|G|314
3G6E|1|0|G|315
3G6E|1|0|A|316
3G6E|1|0|A|317
3G6E|1|0|U|318
3G6E|1|0|A|319

Current chains

Chain 0

23S ribosomal RNA

Nearby chains

Chain C

50S ribosomal protein L4P

Chain T

50S ribosomal protein L24P

Chain Y

50S ribosomal protein L32e