HL_4WOI_137

3D structure

PDB id

4WOI (explore in PDB, NAKB, or RNA 3D Hub)

Description

4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2

Experimental method

X-RAY DIFFRACTION

Resolution

3 Å

Loop

Sequence

GUGAAAAGC

Length

9 nucleotides

Bulged bases

None detected

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_4WOI_137 not in the Motif Atlas

Homologous match to HL_5J7L_165

Geometric discrepancy: 0.1137

The information below is about HL_5J7L_165

Detailed Annotation

T-loop with 2 stacked bulged bases

Broad Annotation

T-loop

Motif group

HL_28252.9

Basepair signature

cWW-tWH-F-F-F-F-F

Number of instances in this motif group

141

Unit IDs

4WOI|1|CA|G|1281
4WOI|1|CA|U|1282
4WOI|1|CA|G|1283
4WOI|1|CA|A|1284
4WOI|1|CA|A|1285
4WOI|1|CA|A|1286
4WOI|1|CA|A|1287
4WOI|1|CA|G|1288
4WOI|1|CA|C|1289

Current chains

Chain CA

23S ribosomal RNA

Nearby chains

Chain C0

50S ribosomal protein L32

Chain CN

50S ribosomal protein L17

Chain CS

50S ribosomal protein L22