HL_5DE8_002

3D structure

PDB id

5DE8 (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form.

Experimental method

X-RAY DIFFRACTION

Resolution

3.1 Å

Loop

Sequence

UGUGGAAGGAGUGGCUGGGUUG

Length

22 nucleotides

Bulged bases

5DE8|1|C|U|10, 5DE8|1|C|A|13, 5DE8|1|C|U|19, 5DE8|1|C|C|22

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_5DE8_002 not in the Motif Atlas

Geometric match to HL_5DEA_002

Geometric discrepancy: 0.1018

The information below is about HL_5DEA_002

Detailed Annotation

G-quadruplex

Broad Annotation

No text annotation

Motif group

HL_60293.1

Basepair signature

cWW-cWH-F-cWH-cHW-cHW-cWH-cHW-cWH-F-cWH-cWH-cWH-F

Number of instances in this motif group

2

Unit IDs

5DE8|1|C|U|8
5DE8|1|C|G|9
5DE8|1|C|U|10
5DE8|1|C|G|11
5DE8|1|C|G|12
5DE8|1|C|A|13
5DE8|1|C|A|14
5DE8|1|C|G|15
5DE8|1|C|G|16
5DE8|1|C|A|17
5DE8|1|C|G|18
5DE8|1|C|U|19
5DE8|1|C|G|20
5DE8|1|C|G|21
5DE8|1|C|C|22
5DE8|1|C|U|23
5DE8|1|C|G|24
5DE8|1|C|G|25
5DE8|1|C|G|26
5DE8|1|C|U|27
5DE8|1|C|U|28
5DE8|1|C|G|29

Current chains

Chain C

sc1

Nearby chains

Chain D

Fragile X mental retardation protein 1