HL_7TOO_014

3D structure

PDB id

7TOO (explore in PDB, NAKB, or RNA 3D Hub)

Description

Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20

Experimental method

ELECTRON MICROSCOPY

Resolution

2.7 Å

Loop

Sequence

UCUUGAAACA

Length

10 nucleotides

Bulged bases

7TOO|1|A25S|C|648

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_7TOO_014 not in the Motif Atlas

Homologous match to HL_8C3A_014

Geometric discrepancy: 0.0942

The information below is about HL_8C3A_014

Detailed Annotation

T-loop with 2 stacked bulged bases

Broad Annotation

T-loop

Motif group

HL_43993.1

Basepair signature

cWW-tWH-F-F-F-F-F

Number of instances in this motif group

141

Unit IDs

7TOO|1|A25S|U|640
7TOO|1|A25S|C|641
7TOO|1|A25S|U|642
7TOO|1|A25S|U|643
7TOO|1|A25S|G|644
7TOO|1|A25S|A|645
7TOO|1|A25S|A|646
7TOO|1|A25S|A|647
7TOO|1|A25S|C|648
7TOO|1|A25S|A|649

Current chains

Chain A25S

25S rRNA

Nearby chains

Chain AL03

RPL3 isoform 1

Chain AL28

60S ribosomal protein L28

Chain AL32

RPL32 isoform 1