HL_7TOP_014

3D structure

PDB id

7TOP (explore in PDB, NAKB, or RNA 3D Hub)

Description

Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20

Experimental method

ELECTRON MICROSCOPY

Resolution

2.4 Å

Loop

Sequence

UCUUGAAACA

Length

10 nucleotides

Bulged bases

7TOP|1|A25S|C|648

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_7TOP_014 not in the Motif Atlas

Homologous match to HL_8C3A_014

Geometric discrepancy: 0.0805

The information below is about HL_8C3A_014

Detailed Annotation

T-loop with 2 stacked bulged bases

Broad Annotation

T-loop

Motif group

HL_43993.1

Basepair signature

cWW-tWH-F-F-F-F-F

Number of instances in this motif group

141

Unit IDs

7TOP|1|A25S|U|640
7TOP|1|A25S|C|641
7TOP|1|A25S|U|642
7TOP|1|A25S|U|643
7TOP|1|A25S|G|644
7TOP|1|A25S|A|645
7TOP|1|A25S|A|646
7TOP|1|A25S|A|647
7TOP|1|A25S|C|648
7TOP|1|A25S|A|649

Current chains

Chain A25S

25S rRNA

Nearby chains

Chain AL03

RPL3 isoform 1

Chain AL28

60S ribosomal protein L28

Chain AL32

RPL32 isoform 1