HL_9IMB_001

3D structure

PDB id

9IMB (explore in PDB, NAKB, or RNA 3D Hub)

Description

The crystal structure of human m5C methyltransferase NSUN6 bound to its S-adenosyl-L-methionine analog and a NECTIN-2 3'-UTR RNA substrate

Experimental method

X-RAY DIFFRACTION

Resolution

2.9 Å

Loop

Sequence

UCAUCUCCAA

Length

10 nucleotides

Bulged bases

9IMB|1|C|C|12, 9IMB|1|C|U|13, 9IMB|1|C|C|14, 9IMB|1|C|C|15, 9IMB|1|C|A|16

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

HL_02621.1

Basepair signature

cWW-F-F-F

Number of instances in this motif group

2

Unit IDs

9IMB|1|C|U|8
9IMB|1|C|C|9
9IMB|1|C|A|10
9IMB|1|C|U|11
9IMB|1|C|C|12
9IMB|1|C|U|13
9IMB|1|C|C|14
9IMB|1|C|C|15
9IMB|1|C|A|16
9IMB|1|C|A|17

Current chains

Chain C

RNA (5'-R(*GP*CP*CP*CP*UP*CP*UP*UP*CP*AP*UP*CP*UP*CP*CP*AP*AP*AP*GP*AP*GP*GP*GP*C)-3')

Nearby chains

Chain A

tRNA (cytosine(72)-C(5))-methyltransferase NSUN6