IL_10PX_238

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

UGCGAAC*GGAGGUAUA

Length

16 nucleotides

Bulged bases

10PX|1|2A|G|1801, 10PX|1|2A|G|1816, 10PX|1|2A|U|1820

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

IL_10PX_238 not in the Motif Atlas

Homologous match to IL_7A0S_065

Geometric discrepancy: 0.1428

The information below is about IL_7A0S_065

Detailed Annotation

Kink-turn related

Broad Annotation

No text annotation

Motif group

IL_17069.6

Basepair signature

cWW-tSH-tHH-cSS-tWW-tHH-tSS-cWW

Number of instances in this motif group

5

Unit IDs

10PX|1|2A|U|1798
10PX|1|2A|G|1799
10PX|1|2A|C|1800
10PX|1|2A|G|1801
10PX|1|2A|A|1802
10PX|1|2A|A|1803
10PX|1|2A|C|1804
*
10PX|1|2A|G|1813
10PX|1|2A|G|1814
10PX|1|2A|A|1815
10PX|1|2A|G|1816
10PX|1|2A|G|1817
10PX|1|2A|U|1818
10PX|1|2A|A|1819
10PX|1|2A|U|1820
10PX|1|2A|A|1821

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 2D

50S ribosomal protein L2

Chain 2a

Small subunit ribosomal RNA; SSU rRNA