IL_5EW4_002

3D structure

PDB id

5EW4 (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of C9ORF72 Antisense CCCCGG repeat RNA associated with Lou Gehrig's disease and frontotemporal dementia, crystallized with Sr2+

Experimental method

X-RAY DIFFRACTION

Resolution

1.47 Å

Loop

Sequence

CCCG*CCCG

Length

8 nucleotides

Bulged bases

None detected

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

Tandem non-canonical cWW pairs

Broad Annotation

No text annotation

Motif group

IL_85033.2

Basepair signature

cWW-cWW-cWW-cWW

Number of instances in this motif group

35

Unit IDs

5EW4|1|A|C|14
5EW4|1|A|C|15
5EW4|1|A|C|16
5EW4|1|A|G|17
*
5EW4|1|B|C|8
5EW4|1|B|C|9
5EW4|1|B|C|10
5EW4|1|B|G|11

Current chains

Chain A

RNA (5'-R(*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*C)-3')

Chain B

RNA (5'-R(*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*C)-3')

Nearby chains