IL_5F9R_003

3D structure

PDB id

5F9R (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of catalytically-active Streptococcus pyogenes CRISPR-Cas9 in complex with single-guided RNA and double-stranded DNA primed for target DNA cleavage

Experimental method

X-RAY DIFFRACTION

Resolution

3.4 Å

Loop

Sequence

GC*GUC

Length

5 nucleotides

Bulged bases

5F9R|1|A|U|77

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

Single bulged U

Broad Annotation

No text annotation

Motif group

IL_83039.19

Basepair signature

cWW-L-cWW

Number of instances in this motif group

123

Unit IDs

5F9R|1|A|G|72
5F9R|1|A|C|73
*
5F9R|1|A|G|76
5F9R|1|A|U|77
5F9R|1|A|C|78

Current chains

Chain A

RNA (116-MER)

Nearby chains

Chain B

CRISPR-associated endonuclease Cas9/Csn1