3D structure

PDB id
6MDZ (explore in PDB, NAKB, or RNA 3D Hub)
Description
Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2)
Experimental method
X-RAY DIFFRACTION
Resolution
3.4 Å

Loop

Sequence
GACAA*UUUCC
Length
10 nucleotides
Bulged bases
6MDZ|1|C|A|10, 6MDZ|1|C|C|11
QA status
Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.
R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.
R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.
R3DMCS Rfam
Detailed Annotation
No text annotation
Broad Annotation
No text annotation
Motif group
IL_58112.2
Basepair signature
cWW-cWW-L-R-cWW
Number of instances in this motif group
4

Unit IDs

6MDZ|1|C|G|9
6MDZ|1|C|A|10
6MDZ|1|C|C|11
6MDZ|1|C|A|12
6MDZ|1|C|A|13
*
6MDZ|1|E|U|9
6MDZ|1|E|U|10
6MDZ|1|E|U|11
6MDZ|1|E|C|12
6MDZ|1|E|C|13

Current chains

Chain C
RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*U)-3')
Chain E
RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3')

Nearby chains

Chain A
Protein argonaute-2

Coloring options:

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