IL_8EPK_004

3D structure

PDB id

8EPK (explore in PDB, NAKB, or RNA 3D Hub)

Description

Complex of anticoagulant RNA aptamer and human coagulation factor IXa (S195A)

Experimental method

X-RAY DIFFRACTION

Resolution

2.65 Å

Loop

Sequence

(A2M)(CFZ)(UFT)(A2M)(UFT)(A2M)(CFZ)(CFZ)(OMG)*(CFZ)(OMU)G(OMC)(CFZ)(UFT)

Length

15 nucleotides

Bulged bases

8EPK|1|F|UFT|9, 8EPK|1|F|CFZ|11, 8EPK|1|F|CFZ|12

QA status

Modified nucleotides: A2M, CFZ, UFT, OMG, OMU, OMC

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

IL_46203.1

Basepair signature

cWW-L-R-L-R-L-R-L-R-cWW

Number of instances in this motif group

2

Unit IDs

8EPK|1|F|A2M|5
8EPK|1|F|CFZ|6
8EPK|1|F|UFT|7
8EPK|1|F|A2M|8
8EPK|1|F|UFT|9
8EPK|1|F|A2M|10
8EPK|1|F|CFZ|11
8EPK|1|F|CFZ|12
8EPK|1|F|OMG|13
*
8EPK|1|F|CFZ|21
8EPK|1|F|OMU|22
8EPK|1|F|G|23
8EPK|1|F|OMC|24
8EPK|1|F|CFZ|25
8EPK|1|F|UFT|26

Current chains

Chain F

RNA (31-MER)

Nearby chains

Chain B

Coagulation factor IXa heavy chain

Chain C

Coagulation factor IXa light chain

Chain D

Coagulation factor IXa heavy chain