J3_10PX_042

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

UAAAC*GGGUCGUG*CG

Length

15 nucleotides

Bulged bases

10PX|1|2A|C|271|||Z, 10PX|1|2A|U|272|||A

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J3_10PX_042 not in the Motif Atlas

Homologous match to J3_7A0S_003

Geometric discrepancy: 0.2786

The information below is about J3_7A0S_003

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

J3_97971.2

Basepair signature

cWW-F-F-tSH-cSH-tWH-tWS-cWW-F-cWW

Number of instances in this motif group

3

Unit IDs

10PX|1|2A|U|269
10PX|1|2A|A|270
10PX|1|2A|A|271
10PX|1|2A|A|271|||A
10PX|1|2A|C|271|||B
*
10PX|1|2A|G|271|||V
10PX|1|2A|G|271|||W
10PX|1|2A|G|271|||X
10PX|1|2A|U|271|||Y
10PX|1|2A|C|271|||Z
10PX|1|2A|G|272
10PX|1|2A|U|272|||A
10PX|1|2A|G|272|||B
*
10PX|1|2A|C|366
10PX|1|2A|G|370

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 21

50S ribosomal protein L28

Chain 2I

50S ribosomal protein L9