J3_10PX_044

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

CGAGCUA*UAG*CGAG

Length

14 nucleotides

Bulged bases

10PX|1|2A|G|686, 10PX|1|2A|G|792, 10PX|1|2A|A|793

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J3_10PX_044 not in the Motif Atlas

Homologous match to J3_7A0S_004

Geometric discrepancy: 0.1551

The information below is about J3_7A0S_004

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

J3_46658.2

Basepair signature

cWW-tWH-cWW-tSW-F-F-cWW

Number of instances in this motif group

11

Unit IDs

10PX|1|2A|C|683
10PX|1|2A|G|684
10PX|1|2A|A|685
10PX|1|2A|G|686
10PX|1|2A|C|687
10PX|1|2A|U|688
10PX|1|2A|A|689
*
10PX|1|2A|U|773
10PX|1|2A|A|774
10PX|1|2A|G|775
*
10PX|1|2A|C|791
10PX|1|2A|G|792
10PX|1|2A|A|793
10PX|1|2A|G|794

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 27

50S ribosomal protein L34

Chain 2D

50S ribosomal protein L2