J3_10PX_052

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

CUC*GAG*UAGAAG

Length

12 nucleotides

Bulged bases

10PX|1|2A|G|2334, 10PX|1|2A|A|2336

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J3_10PX_052 not in the Motif Atlas

Homologous match to J3_7A0S_010

Geometric discrepancy: 0.3144

The information below is about J3_7A0S_010

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

J3_05327.2

Basepair signature

cWW-tWH-tWW-cWW-F-cWW

Number of instances in this motif group

11

Unit IDs

10PX|1|2A|C|2295
10PX|1|2A|U|2296
10PX|1|2A|C|2297
*
10PX|1|2A|G|2321
10PX|1|2A|A|2322
10PX|1|2A|G|2323
*
10PX|1|2A|U|2332
10PX|1|2A|A|2333
10PX|1|2A|G|2334
10PX|1|2A|A|2335
10PX|1|2A|A|2336
10PX|1|2A|G|2337

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 20

50S ribosomal protein L27

Chain 2B

5S ribosomal RNA; 5S rRNA

Chain 2G

50S ribosomal protein L5

Chain 2S

50S ribosomal protein L18

Chain 2x

Transfer RNA; tRNA