J4_10PX_014

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

A(4SU)AG*CAG*CGU(G7M)UCC*GU

Length

16 nucleotides

Bulged bases

10PX|1|1w|4SU|8, 10PX|1|1w|U|47, 10PX|1|1w|C|48

QA status

Modified nucleotides: 4SU, G7M

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J4_10PX_014 not in the Motif Atlas

Homologous match to J4_7U2J_014

Geometric discrepancy: 0.2425

The information below is about J4_7U2J_014

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

Not in a motif group

Basepair signature

Not available

Number of instances in this motif group

0

Unit IDs

10PX|1|1w|A|7
10PX|1|1w|4SU|8
10PX|1|1w|A|9
10PX|1|1w|G|10
*
10PX|1|1w|C|25
10PX|1|1w|A|26
10PX|1|1w|G|27
*
10PX|1|1w|C|43
10PX|1|1w|G|44
10PX|1|1w|U|45
10PX|1|1w|G7M|46
10PX|1|1w|U|47
10PX|1|1w|C|48
10PX|1|1w|C|49
*
10PX|1|1w|G|65
10PX|1|1w|U|66

Current chains

Chain 1w

A-site Aminoacylated Phe-tRNAphe

Nearby chains

Chain 1A

Large subunit ribosomal RNA; LSU rRNA