J4_8K2C_001

3D structure

PDB id

8K2C (explore in PDB, NAKB, or RNA 3D Hub)

Description

Cryo-EM structure of the human 80S ribosome with Tigecycline

Experimental method

ELECTRON MICROSCOPY

Resolution

2.4 Å

Loop

Sequence

GUGG*UGC*GAGGUCG*CC

Length

16 nucleotides

Bulged bases

8K2C|1|CC|U|8, 8K2C|1|CC|U|46, 8K2C|1|CC|C|47

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J4_8K2C_001 not in the Motif Atlas

Homologous match to J4_4V9Q_031

Geometric discrepancy: 0.311

The information below is about J4_4V9Q_031

Detailed Annotation

tRNA junction

Broad Annotation

No text annotation

Motif group

J4_95067.1

Basepair signature

cWW-F-cWW-cWW-cHS-F-cWW-cWW

Number of instances in this motif group

48

Unit IDs

8K2C|1|CC|G|7
8K2C|1|CC|U|8
8K2C|1|CC|G|9
8K2C|1|CC|G|10
*
8K2C|1|CC|U|24
8K2C|1|CC|G|25
8K2C|1|CC|C|26
*
8K2C|1|CC|G|42
8K2C|1|CC|A|43
8K2C|1|CC|G|44
8K2C|1|CC|G|45
8K2C|1|CC|U|46
8K2C|1|CC|C|47
8K2C|1|CC|G|48
*
8K2C|1|CC|C|64
8K2C|1|CC|C|65

Current chains

Chain CC

tRNA-Met

Nearby chains

Chain CE

Coiled-coil domain-containing protein 124

Chain Lo

60S ribosomal protein L36a