3D structure

PDB id
8K2C (explore in PDB, NAKB, or RNA 3D Hub)
Description
Cryo-EM structure of the human 80S ribosome with Tigecycline
Experimental method
ELECTRON MICROSCOPY
Resolution
2.4 Å

Loop

Sequence
AAG*CGAAAG*CCAUAAACGAUG*UU
Length
23 nucleotides
Bulged bases
8K2C|1|S2|A|672, 8K2C|1|S2|A|1083, 8K2C|1|S2|C|1085, 8K2C|1|S2|A|1087
QA status
Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.
R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.
R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.
R3DMCS Rfam
J4_8K2C_015 not in the Motif Atlas
Homologous match to J4_8C3A_022
Geometric discrepancy: 0.0724
The information below is about J4_8C3A_022
Detailed Annotation
No text annotation
Broad Annotation
No text annotation
Motif group
J4_61885.4
Basepair signature
cWW-cWW-cWW-F-F-tHW-F-F-F-F-F-cWW-F-F-F-F
Number of instances in this motif group
5

Unit IDs

8K2C|1|S2|A|671
8K2C|1|S2|A|672
8K2C|1|S2|G|673
*
8K2C|1|S2|C|1032
8K2C|1|S2|G|1033
8K2C|1|S2|A|1034
8K2C|1|S2|A|1035
8K2C|1|S2|A|1036
8K2C|1|S2|G|1037
*
8K2C|1|S2|C|1078
8K2C|1|S2|C|1079
8K2C|1|S2|A|1080
8K2C|1|S2|U|1081
8K2C|1|S2|A|1082
8K2C|1|S2|A|1083
8K2C|1|S2|A|1084
8K2C|1|S2|C|1085
8K2C|1|S2|G|1086
8K2C|1|S2|A|1087
8K2C|1|S2|U|1088
8K2C|1|S2|G|1089
*
8K2C|1|S2|U|1160
8K2C|1|S2|U|1161

Current chains

Chain S2
18S rRNA

Nearby chains

Chain L5
Large subunit ribosomal RNA; LSU rRNA
Chain Ln
60S ribosomal protein L41
Chain Lp
60S ribosomal protein L37a
Chain SL
40S ribosomal protein S11
Chain SN
40S ribosomal protein S13
Chain SO
40S ribosomal protein S14
Chain SW
40S ribosomal protein S15a
Chain SX
40S ribosomal protein S23
Chain Sa
40S ribosomal protein S26

Coloring options:


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