3D structure

PDB id
10PX (explore in PDB, NAKB, or RNA 3D Hub)
Description
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution
Experimental method
X-RAY DIFFRACTION
Resolution
2.45 Å

Loop

Sequence
UUUA*UUUG*CG*CG*CGGAUAAAA
Length
21 nucleotides
Bulged bases
10PX|1|1A|U|2076, 10PX|1|1A|G|2428, 10PX|1|1A|G|2429, 10PX|1|1A|A|2430, 10PX|1|1A|U|2431
QA status
Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.
R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.
R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.
R3DMCS Rfam
J5_10PX_007 not in the Motif Atlas
Homologous match to J5_7A0S_007
Geometric discrepancy: 0.0896
The information below is about J5_7A0S_007
Detailed Annotation
No text annotation
Broad Annotation
No text annotation
Motif group
J5_39529.2
Basepair signature
cWW-cWH-cWH-F-cWW-F-F-cWW-F-cWW-cWW
Number of instances in this motif group
4

Unit IDs

10PX|1|1A|U|2074
10PX|1|1A|U|2075
10PX|1|1A|U|2076
10PX|1|1A|A|2077
*
10PX|1|1A|U|2243
10PX|1|1A|U|2244
10PX|1|1A|U|2245
10PX|1|1A|G|2246
*
10PX|1|1A|C|2258
10PX|1|1A|G|2259
*
10PX|1|1A|C|2281
10PX|1|1A|G|2282
*
10PX|1|1A|C|2427
10PX|1|1A|G|2428
10PX|1|1A|G|2429
10PX|1|1A|A|2430
10PX|1|1A|U|2431
10PX|1|1A|A|2432
10PX|1|1A|A|2433
10PX|1|1A|A|2434
10PX|1|1A|A|2435

Current chains

Chain 1A
23S Ribosomal RNA

Nearby chains

Chain 10
50S ribosomal protein L27
Chain 11
50S ribosomal protein L28
Chain 16
50S ribosomal protein L33
Chain 1D
50S ribosomal protein L2
Chain 1P
50S ribosomal protein L15
Chain 1y
Transfer RNA; tRNA

Coloring options:


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