6AH0 Summary
- Structure title
- The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)
- Authors
- Release date
- 2018-11-14
- Experimental technique
- ELECTRON MICROSCOPY
- Resolution
- 5.7 Å
- Chains
- 5 RNA chains from Homo sapiens
- 52 other chains
- Nucleic acid compounds
- Other compounds
- U5snRNA, U6snRNA, pre-mRNA, U2snRNA, U4snRNA
- Splicing factor 3B subunit 1, Splicing factor 3B subunit 2, Splicing factor 3B subunit 3, Splicing factor 3B subunit 4, Splicing factor 3B subunit 6, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 5, Pre-mRNA-processing-splicing factor 8, 116 kDa U5 small nuclear ribonucleoprotein component, U5 small nuclear ribonucleoprotein 200 kDa helicase, U5 small nuclear ribonucleoprotein 40 kDa protein, U4/U6 small nuclear ribonucleoprotein Prp3, U4/U6 small nuclear ribonucleoprotein Prp4, U4/U6 small nuclear ribonucleoprotein Prp31, NHP2-like protein 1, Pre-mRNA-processing factor 6, Thioredoxin-like protein 4A, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein Sm D1, U4/U6.U5 tri-snRNP-associated protein 2, Probable ATP-dependent RNA helicase DDX23, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein B'', U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, U6 snRNA-associated Sm-like protein LSm5, Splicing factor 3A subunit 1, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, U6 snRNA-associated Sm-like protein LSm8
Pairwise Interactions
Interactions annotated by FR3D:- 117 base-pairs
- 348 base-stacking
- 6 base-phosphate
- 25 base-ribose
- 11 oxygen stacking
- 0 sugar-ribose
RNA 3D Motifs
In the current release of the RNA 3D Motif Atlas, 6AH0 contains:- 7 hairpin loops from 0 motif groups
- 16 internal loops from 0 motif groups
- 1 junction loop from 0 motif groups
3D Redundancy
6AH0 has chains which belong to the following equivalence classes in the current representative set:- NR_all_73286.31 (1)
- NR_all_36640.2 (1)
- NR_20.0_73286.31 (1)
- NR_20.0_36640.2 (1)
Similar structures
9S2E 8I0R 8C6J 7QTT 6ZYM 8I0V 8QOZ 7DVQ 8QPB 8RC0 8I0T 6QDV 6FF4 8Q7Q 7W59 8Q91 7W5A 8Q7N 9S2F 8QP8 8I0U 8QPE 8I0P 6QX9 8RO2 8QZS 8QPA 6ICZ 9FMD 8Q7V 8QPK 8R09 8R0B 7W5B 8I0W 6ID0 6QW6 6ID1 8Q7X 8QP9 6FF7 8Q7W 8QO9 5YZG 8I0S 8CH6 7ABF 5XJC 5MQF 5O9Z 7AAV 8R08 8R0A 6AHD 8RM5 7A5P 5Z56 7ABG 7ABI 5Z58 9R8V 5Z57 8QXD 3JCR 8H6L 8H6K 8H6E 8H6J 8Y6OStructures from NR_all_73286.31