Structure title
Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).
Authors
Release date
2019-04-17
Experimental technique
ELECTRON MICROSCOPY
Resolution
3.3 Å
Chains
6 RNA chains from Homo sapiens, Human mastadenovirus C
65 other chains
Nucleic acid compounds
U1 snRNA, U2 snRNA, U4 snRNA, U5 snRNA, U6 snRNA, AdML pre-mRNA
Other compounds
Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D3, U1 small nuclear ribonucleoprotein A, U1 small nuclear ribonucleoprotein C, U1 small nuclear ribonucleoprotein 70 kDa, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D3, U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein B'', Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D3, U4/U6 small nuclear ribonucleoprotein Prp3, U4/U6 small nuclear ribonucleoprotein Prp4, U4/U6 small nuclear ribonucleoprotein Prp31, NHP2-like protein 1, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D3, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, 116 kDa U5 small nuclear ribonucleoprotein component, Thioredoxin-like protein 4A, Pre-mRNA-processing factor 6, U5 small nuclear ribonucleoprotein 40 kDa protein, Probable ATP-dependent RNA helicase DDX23, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, U6 snRNA-associated Sm-like protein LSm5, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, U6 snRNA-associated Sm-like protein LSm8, Splicing factor 3A subunit 1,Splicing factor 3A subunit 1,Splicing factor 3A subunit 1, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, Splicing factor 3B subunit 1, Splicing factor 3B subunit 2, Splicing factor 3B subunit 3, Splicing factor 3B subunit 4, Splicing factor 3B subunit 5, PHD finger-like domain-containing protein 5A, Serine/threonine-protein kinase PRP4 homolog, RNA-binding protein 42, U4/U6.U5 tri-snRNP-associated protein 1, U4/U6.U5 tri-snRNP-associated protein 2, U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

Pairwise Interactions

Interactions annotated by FR3D: View all

RNA 3D Motifs

In the current release of the RNA 3D Motif Atlas, 6QX9 contains:
  • 9 hairpin loops from 0 motif groups
  • 19 internal loops from 0 motif groups
  • 2 junction loops from 0 motif groups
More

3D Redundancy

6QX9 has chains which belong to the following equivalence classes in the current representative set:

Similar structures

None found
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