7SYS Summary
- Structure title
- Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII).
- Authors
- Brown, Z.P., Abaeva, I.S., De, S., Hellen, C.U.T., Pestova, T.V., Frank, J.
- Release date
- 2022-07-27
- Experimental technique
- ELECTRON MICROSCOPY
- Resolution
- 3.5 Å
- Chains
- 3 RNA chains from Oryctolagus cuniculus, Hepatitis C virus (isolate 1)
- 36 other chains
- Nucleic acid compounds
- Other compounds
- 18S rRNA, Met-tRNA-i-Met, HCV IRES
- Eukaryotic translation initiation factor 1A, X-chromosomal, uS2 (SA), eS1, uS5, uS3, eS4 (S4 X isoform), uS7, eS6, eS7, eS8, uS4, eS10, uS17, eS12, uS15, uS11, uS19, uS9, eS17, uS13, eS19, uS10, eS21, uS8, uS12, eS24, eS25, eS26, eS27, eS28, uS14, eS30, eS31, Receptor for Activated C Kinase 1 (RACK1), Eukaryotic translation initiation factor 2 subunit 1, eL41
Pairwise Interactions
Interactions annotated by FR3D:- 616 base-pairs
- 1,785 base-stacking
- 31 base-phosphate
- 32 base-ribose
RNA 3D Motifs
In the current release of the RNA 3D Motif Atlas, 7SYS contains:- 48 hairpin loops from 0 motif groups
- 112 internal loops from 0 motif groups
- 29 junction loops from 0 motif groups
3D Redundancy
7SYS has chains which belong to the following equivalence classes in the current representative set:- NR_all_21280.40 (1)
- NR_all_77343.6 (1)
- NR_all_12406.6 (1)
- NR_4.0_21280.40 (1)
- NR_4.0_77343.6 (1)
- NR_4.0_12406.6 (1)
- NR_3.5_21280.40 (1)
- NR_3.5_77343.6 (1) rep
- NR_3.5_12406.6 (1) rep
- NR_20.0_21280.40 (1)
- NR_20.0_77343.6 (1)
- NR_20.0_12406.6 (1)
Similar structures
7O7Z 8SCB 7JQB 7UCK 8VVQ 9QQA 9BDL 8P03 7NWI 8P2K 8VVP 6W2T 9BDN 9F1B 6P4H 7ZJX 6P4G 8P09 7TOR 7O81 6W2S 6MTC 6MTD 7UCJ 6P5I 9F1D 6P5N 7SYW 5LZV 6MTE 9QQB 7JQC 8BHF 6YAL 6MTB 6P5K 7SYQ 5LZZ 6D90 5LZS 6YAN 6ZVK 8VVR 7NWG 6HCF 7SYR 9F1C 8VVS 7SYX 5LZW 5LZT 7SYN 6R5Q 7MDZ 7SYV 6D9J 9BDP 3JAH 8VVT 6R6P 8VFT 6GZ5 6GZ4 7SYK 5LZU 7SYP 3JAG 6P5J 7SYU 7SYG 6GZ3 5LZY 7TOQ 6YAM 3JAI 7SYL 9C8K 8VVV 7SYT 6R6G 7SYM 7SYJ 7SYI 7NWH 7SYO 7A01 5FLX 6HCJ 6R7Q 7SYH 5K0Y 5LZX 8VVU 6HCQ 9CPA 6HCM 4KZY 4KZZ 4KZX 4UJE 4D5L 4D61 4UJC 3JAJ 4UJD 3JAN 7O7Y 7ZJW 7O80 6SGC 8BTK 7OYDStructures from NR_all_21280.40