Structure title
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
Authors
Cretu, C., Schmitzova, J., Pena, V.
Release date
2023-05-10
Experimental technique
ELECTRON MICROSCOPY
Resolution
5.9 Å
Chains
4 RNA chains from Homo sapiens, unidentified adenovirus
55 other chains
Nucleic acid compounds
RNU6-1, RNU5A-1, RNU2-1, MINX-M3
Other compounds
Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein G, Splicing factor 3B subunit 3, Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 2, Splicing factor 3B subunit 4, G-patch domain and KOW motifs-containing protein, Splicing factor 3A subunit 1, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, Pre-mRNA-processing factor 19, BUD13 homolog, Pre-mRNA-processing factor 19, Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16, Pleiotropic regulator 1, Cell division cycle 5-like protein, Spliceosome-associated protein CWC15 homolog, Pre-mRNA-processing factor 19, Pre-mRNA-splicing factor SPF27, Protein BUD31 homolog, Pre-mRNA-splicing factor RBM22, Peptidyl-prolyl cis-trans isomerase-like 4, Pre-mRNA-splicing factor CWC22 homolog, Crooked neck-like protein 1, SNW domain-containing protein 1, RING finger protein 113A, Pre-mRNA-processing-splicing factor 8, 116 kDa U5 small nuclear ribonucleoprotein component, U5 small nuclear ribonucleoprotein 200 kDa helicase, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein-associated proteins B and B', U5 small nuclear ribonucleoprotein 40 kDa protein, Peptidyl-prolyl cis-trans isomerase-like 1, Serine/arginine repetitive matrix protein 2, U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein B'', Pre-mRNA-splicing factor ISY1 homolog, RING-type E3 ubiquitin-protein ligase PPIL2, Pre-mRNA-processing factor 19, Peptidyl-prolyl cis-trans isomerase E, Pre-mRNA-processing factor 17, Intron-binding protein aquarius, Pre-mRNA-splicing factor SYF1

Pairwise Interactions

Interactions annotated by FR3D: View all

RNA 3D Motifs

In the current release of the RNA 3D Motif Atlas, 8CH6 contains:
  • 9 hairpin loops from 0 motif groups
  • 16 internal loops from 0 motif groups
  • 0 junction loops from 0 motif groups
More

3D Redundancy

8CH6 has chains which belong to the following equivalence classes in the current representative set:

Similar structures

None found
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