Structure title
Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.
Authors
Zhang, W., Zhan, X., Zhang, X., Bai, R., Lei, J., Yan, C., Shi, Y.
Release date
2024-05-01
Experimental technique
ELECTRON MICROSCOPY
Resolution
3.2 Å
Chains
5 RNA chains from Homo sapiens
56 other chains
Nucleic acid compounds
U2 snRNA, U4 snRNA, U5 snRNA, U6 snRNA, pre-mRNA
Other compounds
U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein B'', Splicing factor 3A subunit 1, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, Splicing factor 3B subunit 1, Splicing factor 3B subunit 2, Splicing factor 3B subunit 3, Splicing factor 3B subunit 4, Splicing factor 3B subunit 6, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 5, Isoform SM-B of Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D3, U4/U6 small nuclear ribonucleoprotein Prp3, U4/U6 small nuclear ribonucleoprotein Prp4, U4/U6 small nuclear ribonucleoprotein Prp31, NHP2-like protein 1, Thioredoxin-like protein 4A, Pre-mRNA-processing factor 6, RNA-binding protein 42, U4/U6.U5 tri-snRNP-associated protein 1, U4/U6.U5 tri-snRNP-associated protein 2, Probable ATP-dependent RNA helicase DDX23, U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein, Serine/threonine-protein kinase PRP4 homolog, Isoform SM-B of Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D3, Pre-mRNA-processing-splicing factor 8, 116 kDa U5 small nuclear ribonucleoprotein component, U5 small nuclear ribonucleoprotein 200 kDa helicase, U5 small nuclear ribonucleoprotein 40 kDa protein, Isoform SM-B of Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D3, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, U6 snRNA-associated Sm-like protein LSm5, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, U6 snRNA-associated Sm-like protein LSm8

Pairwise Interactions

Interactions annotated by FR3D: View all

RNA 3D Motifs

In the current release of the RNA 3D Motif Atlas, 8H6E contains:
  • 5 hairpin loops from 0 motif groups
  • 16 internal loops from 0 motif groups
  • 0 junction loops from 0 motif groups
More

3D Redundancy

8H6E has chains which belong to the following equivalence classes in the current representative set:

Similar structures

None found
Copyright 2025 BGSU RNA group. Page generated in 0.174 s