8QO9 Summary
- Structure title
- Cryo-EM structure of a human spliceosomal B complex protomer
- Authors
- Zhang, Z., Kumar, V., Dybkov, O., Will, C.L., Urlaub, H., Stark, H., Luehrmann, R.
- Release date
- 2024-01-24
- Experimental technique
- ELECTRON MICROSCOPY
- Resolution
- 5.3 Å
- Chains
- 5 RNA chains from Homo sapiens
- 66 other chains
- Nucleic acid compounds
- Other compounds
- U2 snRNA, U4 snRNA, U5 snRNA, U6 snRNA, MINX pre-mRNA
- Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D3, U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein B'', Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, U6 snRNA-associated Sm-like protein LSm5, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, U6 snRNA-associated Sm-like protein LSm8, Splicing factor 3A subunit 1, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, Splicing factor 3B subunit 1, Splicing factor 3B subunit 2, Splicing factor 3B subunit 3, Splicing factor 3B subunit 4, Splicing factor 3B subunit 5, Splicing factor 3B subunit 6, PHD finger-like domain-containing protein 5A, 116 kDa U5 small nuclear ribonucleoprotein component, Thioredoxin-like protein 4A, U5 small nuclear ribonucleoprotein 40 kDa protein, U4/U6 small nuclear ribonucleoprotein Prp4, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, Pre-mRNA-splicing factor 38A, U4/U6 small nuclear ribonucleoprotein Prp3, Microfibrillar-associated protein 1, U4/U6 small nuclear ribonucleoprotein Prp31, NHP2-like protein 1, N-terminally processed, Pre-mRNA-processing factor 6, Protein BUD31 homolog, U4/U6.U5 tri-snRNP-associated protein 1, Transcription elongation regulator 1, Peptidyl-prolyl cis-trans isomerase H, WW domain-binding protein 4, Zinc finger matrin-type protein 2, Ubiquitin-like protein 5, WD40 repeat-containing protein SMU1, WD40 repeat-containing protein SMU1, Protein Red, Protein Red, Serine/arginine-rich splicing factor 1
Pairwise Interactions
Interactions annotated by FR3D:- 127 base-pairs
- 390 base-stacking
- 3 base-phosphate
- 3 base-ribose
RNA 3D Motifs
In the current release of the RNA 3D Motif Atlas, 8QO9 contains:- 6 hairpin loops from 0 motif groups
- 19 internal loops from 0 motif groups
- 1 junction loop from 0 motif groups
3D Redundancy
8QO9 has chains which belong to the following equivalence classes in the current representative set:- NR_all_73286.29 (1)
- NR_all_36640.2 (1)
- NR_20.0_73286.29 (1)
- NR_20.0_36640.2 (1)