8SUP Summary
- Structure title
- Structure of the 48S translation initiation complex assembled on the encephalomyocarditis virus IRES
- Authors
- Bhattacharjee, S., Abaeva, I.S., Brown, Z.P., Arhab, Y., Fallah, H., Jeevan, J.C., Hellen, C.U.T., Frank, J., Pestova, T.V.
- Release date
- 2026-03-18
- Experimental technique
- ELECTRON MICROSCOPY
- Resolution
- 3.1 Å
- Chains
- 3 RNA chains from Oryctolagus cuniculus, Encephalomyocarditis virus
- 44 other chains
- Nucleic acid compounds
- Other compounds
- 18S rRNA, EMCV mRNA, Met-tRNAiMet
- Eukaryotic translation initiation factor 1A, X-chromosomal, uS2 (SA), eS1, 40S ribosomal protein S2, uS3, eS4 (S4 X isoform), uS7, eS6, eS7, eS8, uS4, eS10, uS17, eS12, uS15, Small ribosomal subunit protein uS11, uS19, uS9, eS17, uS13, eS19, uS10, eS21, uS8, uS12, eS24, eS25, eS26, eS27, eS28, uS14, eS30, eS31, Receptor for Activated C Kinase 1 (RACK1), Eukaryotic translation initiation factor 2 subunit 1, eL41, Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit E, Eukaryotic translation initiation factor 3 subunit F, Eukaryotic translation initiation factor 3 subunit H, Eukaryotic translation initiation factor 3 subunit K, Eukaryotic translation initiation factor 3 subunit L, Eukaryotic translation initiation factor 3 subunit M
Pairwise Interactions
Interactions annotated by FR3D:- 615 base-pairs
- 1,705 base-stacking
- 182 base-phosphate
- 198 base-ribose
- 79 oxygen stacking
- 73 sugar-ribose
RNA 3D Motifs
In the current release of the RNA 3D Motif Atlas, 8SUP contains:- 36 hairpin loops from 0 motif groups
- 94 internal loops from 0 motif groups
- 23 junction loops from 0 motif groups
3D Redundancy
8SUP has chains which belong to the following equivalence classes in the current representative set:- NR_all_21280.49 (1)
- NR_all_77343.7 (1) rep
- NR_all_36274.1 (1) rep
- NR_4.0_21280.49 (1)
- NR_4.0_77343.7 (1) rep
- NR_4.0_36274.1 (1) rep
- NR_3.5_21280.49 (1)
- NR_3.5_77343.7 (1) rep
- NR_3.5_36274.1 (1) rep
- NR_20.0_21280.49 (1)
- NR_20.0_77343.7 (1) rep
- NR_20.0_36274.1 (1) rep
Similar structures
7O7Z 8SCB 9RHU 9YPZ 9YQ1 9YQ0 7JQB 9YPY 9YPW 7UCK 8VVQ 9QQA 9H6Y 9YPG 9BDL 8P03 9YPO 9YPS 9YPV 7NWI 8P2K 9YPT 9H74 8VVP 6W2T 9BDN 9F1B 6P4H 7ZJX 6P4G 8P09 7TOR 7O81 7SYS 6W2S 9NDP 6MTC 6MTD 7UCJ 9MR4 6P5I 9F1D 6P5N 7SYW 5LZV 6MTE 9QQB 7JQC 8BHF 6YAL 6MTB 6P5K 7SYQ 5LZZ 6D90 5LZS 6YAN 6ZVK 8VVR 7NWG 6HCF 7SYR 9F1C 8VVS 7SYX 5LZW 5LZT 7SYN 6R5Q 7MDZ 7SYV 6D9J 9BDP 3JAH 8VVT 6R6P 8VFT 6GZ5 6GZ4 7SYK 5LZU 7SYP 3JAG 6P5J 7SYU 7SYG 6GZ3 5LZY 7TOQ 6YAM 3JAI 7SYL 9C8K 8VVV 7SYT 6R6G 7SYM 7SYJ 7SYI 7NWH 7SYO 7A01 5FLX 6HCJ 6R7Q 7SYH 9OGY 5K0Y 5LZX 8VVU 6HCQ 9CPA 6HCM 4KZY 4KZZ 4KZX 4UJE 4D5L 4D61 4UJC 3JAJ 4UJD 3JAN 7O7Y 7ZJW 7O80 6SGC 8BTK 7OYDStructures from NR_all_21280.49