Changes in PDB files used for clustering

Release 1.4 has 202 PDB files, release 1.5 has 204 PDB files, 201 of them are identical.

1 equivalence classes changed representatives: 2XZM4BPP.

2 new structures in release 1.5: 4K31, 4LCK.

Obsolete: 2XZM4V5O.

Help Every Motif Atlas release is based on a representative set of PDB files. When comparing two releases, it's important to know how the input data changed.

Representative sets are quite stable in time, but PDB files from the older releases can be replaced by newer PDB files or removed from the set altogether if the structure is obsoleted by PDB without replacement.

PDB files from the newer release either replace representatives in the existing equivalence classes or come from new equivalence classes.

Redistribution of motif instances

Loading the Sankey diagram...

Changes in motif groups

Release 1.4 has 271 motif groups, release 1.5 has 274 motif groups, 189 of them are identical.

43 motif groups were updated, 39 groups are present only in release 1.4, 42 groups are only in release 1.5.

Help The Sankey diagram shows redistribution of motif instances (loops) between two releases. The rectangles represent the motif groups and are colored as follows:

Added motif groups: green
Removed motif groups: grey
Updated motif groups: orange
Added motif instances: green
Removed motif instances: grey

Hover over the links connecting the motif groups to see which motif instances were exchanged.


Identical motif groups

#Motif idInstancesDescription
1IL_56465.346Single, unpaired intercalated base, consensus A
2IL_28947.12123S H91 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
3IL_92027.31716S h21 S8 binding site
4IL_85647.316Sarcin-ricin parent motif with 15 Nts
5IL_43124.11123S H73 ILa : Part of larger Motif | Single sheared with bulged bases
6IL_90459.39cWW AG or UU
7IL_02809.29REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
8IL_92114.39GAAA loop receptor "platform" motif
9IL_47444.39SRP Loop E-like motif
10IL_73000.27cHS-cWS
11IL_25230.36Bacterial 5S rRNA Loop E
12IL_70237.36
13IL_72158.36LSU Helix 62 (H62) IL
14IL_97057.36
15IL_53635.36LSU Helix 32 (H32) IL
16IL_39585.16Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
17IL_13069.36LSU 3WJ H32-H33-H35A
18IL_86357.35LSU Helix 61 IL2
19IL_02359.35
20IL_79083.35
21IL_25300.1516S h19 IL and 23S H41 IL
22IL_71288.15Leadzyme Motif. LSU H101 IL2. SSU Decoding site.
23IL_42251.14
24IL_38807.34
25IL_39526.44
26IL_01080.14
27IL_34363.24Kink-turn from 23S H42
28IL_98591.34
29IL_93568.24Triple Sheared (tSH-tHS-tHS) with wobble cWW.
30IL_22732.14tSH-inserted-tHS
31IL_21333.24tSH-tHW-bulge
32IL_05723.13
33IL_37053.13Kink-turn from 23S H58
34IL_75447.13
35IL_43946.13
36IL_82563.13Thi-box riboswitch T-loop
37IL_48918.23Kink-turn variant
38IL_34628.23Kink-turn
39IL_79955.23SSU Helix (23) h23 IL1
40IL_58586.23
41IL_74876.23Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
42IL_09520.23Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW
43IL_80348.1323S H91 IL
44IL_52173.13
45IL_80494.23LSU H58 IL2 H.m.
46IL_50521.12
47IL_12211.12
48IL_00998.12
49IL_69536.12LSU Helix 96 (H96) IL2
50IL_87548.12
51IL_55287.12
52IL_78744.12Quadruple Sheared (tSH-tSH-tHS-tHS)
53IL_52940.12
54IL_09882.12
55IL_77076.12
56IL_09587.12
57IL_96446.12
58IL_31707.12Vitamin B12 aptamer
59IL_90057.12
60IL_21495.12
61IL_37406.12
62IL_23414.12
63IL_37197.12
64IL_33964.12
65IL_19898.12
66IL_98566.12
67IL_45794.12
68IL_65137.12Kink-turn like motif in Group I Intron
69IL_46435.12
70IL_01054.12
71IL_15840.22Triple Sheared with unpaired, inserted A
72IL_23262.42
73IL_16330.12
74IL_11751.12
75IL_97833.12
76IL_09348.52Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW
77IL_80093.12
78IL_40892.12
79IL_76095.32Motif from Hairpin Ribozyme
80IL_57785.52SSU Decoding Site -- Human. Bulge-cSW-tHS
81IL_94744.12Sarcin-ricin motif with extra cWW GA pair
82IL_85805.11
83IL_92280.11
84IL_57977.11
85IL_82650.11
86IL_66744.11SSU Helix 21 (h21) IL2 E.coli
87IL_27243.11
88IL_75328.11
89IL_83856.11
90IL_53323.11
91IL_26971.11
92IL_09491.11
93IL_64589.11
94IL_91089.11
95IL_94973.11Sarcin-Ricin from Group II Intron with inserted base and poor modeling:
96IL_47732.11
97IL_83250.1116S h40 3WJ T.th.
98IL_41791.11
99IL_25307.11
100IL_59934.11SSU Helix 23 (h23) Kink-turn E. coli
101IL_52509.11
102IL_61730.11
103IL_81398.11
104IL_98924.11
105IL_59529.11
106IL_02957.11
107IL_82601.11Tandem cWW water-inserted CU pairs
108IL_23448.11
109IL_57285.11
110IL_30354.11
111IL_63952.11
112IL_03110.11
113IL_76263.11
114IL_91379.11
115IL_52958.11
116IL_78809.11
117IL_13682.11
118IL_25082.11
119IL_71685.11Sarcin-like with an intercalated basepair
120IL_25181.11
121IL_17682.11Sarcin-ricin motif from Eukaryal LSU Helix 11
122IL_60643.11
123IL_46721.11
124IL_86981.11Sarcin-ricin motif with CC BIfurcated pair. H.m. LSU H18.
125IL_68827.11Reverse Kink-Turn
126IL_83920.11
127IL_06468.1116S h40 3WJ E.c.
128IL_11778.11
129IL_54576.11
130IL_54954.11Sarcin-Ricin with extra tSH UA basepair. Yeast LSU H11.
131IL_23639.11tWH-tHS-L-cWW
132IL_15205.11
133IL_91044.11
134IL_27668.11
135IL_88865.11
136IL_39324.11
137IL_86059.11
138IL_97191.11Sarcin-ricin motif with cWW UU instead of tSH basepair.
139IL_47687.11
140IL_31006.11tSH-tHW-L-bif-cWW
141IL_55649.11
142IL_20775.11tSH-inserted
143IL_75415.11Pseudo-knot forming internal loop
144IL_76486.11Sarcin-ricin motif with syn G
145IL_37990.11
146IL_17603.11
147IL_85510.11
148IL_06847.11Group II Intron IL
149IL_30067.11
150IL_09333.11SSU Helix 8 (h8) IL T. thermophilus
151IL_02835.11
152IL_28644.11
153IL_06808.11Double sheared (tSH-tSH) one bulged base.
154IL_03741.11
155IL_97842.11
156IL_98655.11Part of H71 Junction in 26S rRNA from Yeast
157IL_56513.11
158IL_88367.11
159IL_60649.11Kink-turn
160IL_52610.11
161IL_21254.11SSU Helix 11 (h11) IL Kink-turn T. thermophilus
162IL_12507.11
163IL_26868.11
164IL_89794.11
165IL_80652.11
166IL_54450.11
167IL_77014.11
168IL_91078.11
169IL_37347.11
170IL_46306.11
171IL_21421.11
172IL_40527.11Kink-turn
173IL_77296.11
174IL_87394.11
175IL_40845.11
176IL_43316.11
177IL_80505.11
178IL_11302.11
179IL_53988.11
180IL_31754.11Sarcin-ricin H95 23S rRNA E.c.
181IL_71942.11
182IL_06306.11
183IL_05221.11
184IL_06471.11
185IL_91904.11
186IL_58454.11
187IL_41139.11
188IL_03282.11
189IL_42891.11

Updated motif groups

#Motif idInstancesDescription
1IL_97217.72431-3 bulged nucleotides, same chain | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
2IL_47174.8205cWW AG or water inserted cWW Y-Y.
3IL_39199.453Hoogsteen-edge Platform, Single bulged base
4IL_41766.449Tandem cWW pairs (Not AU or GC)
5IL_44540.443Sugar-edge, 1-base platform, consensus tHS
6IL_87904.531Triple sheared (tSH-tHS-tHS) no inserted bases
7IL_13959.426Double Sheared (tSH-tHS)
8IL_65553.622Kink-turn
9IL_93424.421tSH-inserted-tHW
10IL_73276.421C-loop
11IL_55938.418LSU Helix 89 (H89) IL2. cSH Platform.
12IL_24982.516SSU helix 20 (h20) IL. Prokaryal 5S Loop E Sub-motif
13IL_94430.51616S h32-h33-h34 3WJ
14IL_92109.215cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
15IL_31555.413Tandem sheared with inserted, unpaired purine.
16IL_49493.413Sarcin-ricin Parent Motif - bacterial LSU H95 IL
17IL_24546.41023S H41 IL and 16S h18 IL : Has large bulge on one side
18IL_58291.410Recurrent Sub-motif found in junctions
19IL_46648.31023S H91 IL | Single-Base Intercalation Site
20IL_40090.510Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
21IL_83451.37cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
22IL_92321.47Triple sheared (tSH-tHS-tHS) with cWW Wobble base flanking motif
23IL_77263.26Kink-turn from U4
24IL_08926.3623S H91 IL
25IL_90133.36
26IL_44067.45Quadruple sheared (tSH-tHS-tHS-tHS). LSU Helix 2 (H2).
27IL_31066.34SSU Helix 44 (h44) extension
28IL_45262.44
29IL_28572.2416S h18 kink-turn like motif
30IL_82188.24LSU H68 IL from H.m.
31IL_95652.34SSU Helix 27 (h27) IL Sarcin-Ricin motif
32IL_71565.44
33IL_47758.24REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
34IL_07300.23
35IL_95150.43
36IL_16415.23SSU Helix 23 (h23) Kink-turn T. thermophilus
37IL_94403.23LSU H77
38IL_25271.23SSU Helix 8 (h8) IL E.c. and Yeast
39IL_98421.43SSU Helix 12 (h12) IL
40IL_62499.73
41IL_89028.63Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
42IL_16166.4323S H91 IL
43IL_30840.23

Removed motif groups

#Motif idInstancesDescription
1IL_06390.326cWH basepair with syn base
2IL_21304.211Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
3IL_54420.16
4IL_16207.15Single sheared with bulged bases
5IL_92484.15
6IL_78732.35Double S-turn motif
7IL_08559.14LSU Helix 89 (H89) IL2
8IL_56077.13
9IL_92267.1323S H73 ILa : Part of larger Motif
10IL_34156.63cWW AG or UU
11IL_10647.13tHS tHH bulge with S-turn
12IL_28942.12
13IL_91273.12
14IL_16252.3223S H91 IL
15IL_33925.12
16IL_09901.12tHS tHH bulge with S-turn
17IL_70280.12Double sheared with wobble cWW.
18IL_24358.12
19IL_27892.12
20IL_49550.12tHS tHH bulge with S-turn
21IL_88180.12cWW-bulge-cWW
22IL_04550.11tHS tHH bulge with S-turn
23IL_15674.11Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
24IL_05462.11
25IL_31290.11
26IL_65788.11
27IL_21221.11SSU Helix 12 (h12) IL
28IL_67735.11
29IL_95774.11tHS tHH bulge with S-turn
30IL_34868.11LSU Eukaryal Helix 96 (H96) IL1
31IL_97073.11
32IL_37715.11
33IL_02690.11
34IL_12486.11
35IL_41341.11Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
36IL_82113.11
37IL_03931.1116S h19 IL and 23S H41 IL
38IL_13434.11
39IL_28468.11Single sheared with bulged bases

Added motif groups

#Motif idInstancesDescription
1IL_82444.129cWH basepair with syn base | cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
2IL_37104.111Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
3IL_25380.16LSU Helix 89 (H89) IL2
4IL_05684.15tHS tHH bulge with S-turn | Double S-turn motif
5IL_39980.14
6IL_09530.14Double S-turn motif
7IL_15768.14cWW AG or UU | cWH basepair with syn base
8IL_31663.1423S H73 ILa : Part of larger Motif
9IL_06180.13tHS tHH bulge with S-turn
10IL_06211.13
11IL_87065.1323S H91 IL | Single-Base Intercalation Site
12IL_35994.12cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
13IL_87507.12tHS tHH bulge with S-turn
14IL_21639.12
15IL_39355.12SSU Helix 12 (h12) IL | LSU Eukaryal Helix 96 (H96) IL1
16IL_67887.12
17IL_90735.12
18IL_30381.12tHS tHH bulge with S-turn
19IL_46034.12
20IL_12685.12cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
21IL_96206.12
22IL_97509.12Double sheared with wobble cWW.
23IL_35595.1223S H73 ILa : Part of larger Motif | Single sheared with bulged bases
24IL_06177.11cWW AG or UU
25IL_20530.11
26IL_54470.11tHS tHH bulge with S-turn
27IL_21077.11
28IL_57364.11LSU Helix 89 (H89) IL2
29IL_87523.11
30IL_59018.11
31IL_88119.11
32IL_06421.11Single sheared with bulged bases
33IL_68767.11
34IL_96182.11cWH basepair with syn base
35IL_31224.1123S H91 IL
36IL_49527.11
37IL_69799.11
38IL_02897.11Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
39IL_49976.11
40IL_18675.11cWW-bulge-cWW
41IL_50911.1116S h34 ILa : Part of larger motif
42IL_99438.11