#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
12P7E|1|D+ 2P7E|1|C+ 2P7E|1|P (rep)3' substrate strand, octameric fragment, Ribozyme strand II, Ribozyme strand IIIVanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State StabilizationX-ray diffraction2.052007-05-22
22NPY|1|D+ 2NPY|1|C+ 2NPY|1|A+ 2NPY|1|B5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(U2N)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal Structure of a junctioned hairpin ribozyme incorporating 9atom linker and 2'-deoxy 2'-amino U at A-1X-ray diffraction2.652007-08-14
31ZFT|1|D+ 1ZFT|1|C+ 1ZFT|1|A+ 1ZFT|1|B5'-R(*CP*GP*GP*UP*GP*AP*IP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'The crystal structure of an all-RNA minimal Hairpin Ribozyme with mutant G8I at the cleavage siteX-ray diffraction2.332006-02-14
42P7F|1|D+ 2P7F|1|C+ 2P7F|1|A+ 2P7F|1|BLoop A ribozyme strand, Loop B ribozyme strand, Loop B S-turn strand, substrate strandThe Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small RibozymeX-ray diffraction2.352007-05-22
51ZFV|1|D+ 1ZFV|1|C+ 1ZFV|1|A+ 1ZFV|1|B5'-R(*CP*GP*GP*UP*GP*AP*AP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'The structure of an all-RNA minimal Hairpin Ribozyme with Mutation G8A at the cleavage siteX-ray diffraction2.42006-02-14
62OUE|1|D+ 2OUE|1|C+ 2OUE|1|A+ 2OUE|1|BLoop A ribozyme strand, Loop B ribozyme strand, Loop B S-turn strand, Substrate strand - Minimal Junctionless Hairpin RibozymeCrystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolutionX-ray diffraction2.052007-03-06
72P7D|1|D+ 2P7D|1|C+ 2P7D|1|P3' substrate strand, octameric fragment, Ribozyme strand II, Ribozyme strand IIIA Minimal, 'Hinged' Hairpin Ribozyme Construct Solved with Mimics of the Product Strands at 2.25 Angstroms ResolutionX-ray diffraction2.252007-05-22
82D2L|1|D+ 2D2L|1|C+ 2D2L|1|A+ 2D2L|1|B5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*(P1P)P*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal Structure of a minimal, all-RNA hairpin ribozyme with a propyl linker (C3) at position U39X-ray diffraction2.52005-11-01
92FGP|1|D+ 2FGP|1|C+ 2FGP|1|A+ 2FGP|1|B5'-R(*CP*GP*GP*UP*GP*AP*(N6G)P*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C) -3'Crystal structure of a minimal, all RNA hairpin ribozyme with modifications (g8dap, u39c) at ph 8.6X-ray diffraction2.42006-02-14
101X9C|1|D+ 1X9C|1|C+ 1X9C|1|A+ 1X9C|1|B5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'An all-RNA Hairpin Ribozyme with mutation U39CX-ray diffraction2.192005-11-22
111ZFX|1|D+ 1ZFX|1|C+ 1ZFX|1|A+ 1ZFX|1|B5'-R(*CP*GP*GP*UP*GP*AP*UP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'The Structure of a minimal all-RNA Hairpin Ribozyme with the mutant G8U at the cleavage siteX-ray diffraction2.382006-02-14
122BCZ|1|D+ 2BCZ|1|C+ 2BCZ|1|A+ 2BCZ|1|B5'-R(*CP*GP*GP*UP*GP*AP*IP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(DA)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8I, 2'deoxy A-1)X-ray diffraction2.42006-02-14
132D2K|1|D+ 2D2K|1|C+ 2D2K|1|A+ 2D2K|1|B5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*UP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal Structure of a minimal, native (U39) all-RNA hairpin ribozymeX-ray diffraction2.652005-11-01
142BCY|1|D+ 2BCY|1|C+ 2BCY|1|A+ 2BCY|1|B5'-R(*CP*GP*GP*UP*GP*AP*(MTU)P*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8MTU)X-ray diffraction2.72006-02-14
154G6R|1|D+ 4G6R|1|C+ 4G6R|1|A+ 4G6R|1|BLoop A Ribozyme strand, Loop A Substrate strand, Loop B Ribozyme Strand, Loop B S-turn strandMinimal Hairpin Ribozyme in the Transition State with G8I VariationX-ray diffraction2.832012-08-15
163GS8|1|D+ 3GS8|1|C+ 3GS8|1|A+ 3GS8|1|BRNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), RNA (5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'), RNA (5'-R(P*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3')An all-RNA hairpin ribozyme A38N1dA38 variant with a transition-state mimic substrate strandX-ray diffraction2.852009-04-21
173GS1|1|D+ 3GS1|1|C+ 3GS1|1|A+ 3GS1|1|BRNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), RNA (5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'), RNA (5'-R(P*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3')An all-RNA Hairpin Ribozyme with mutation A38N1dAX-ray diffraction2.852009-05-12
183CR1|1|CRNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*CP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3')crystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2X-ray diffraction2.252008-08-26
193I2Q|1|C5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A9X-ray diffraction2.92009-11-03
203I2S|1|C5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10X-ray diffraction2.752009-11-03
213CQS|1|C19-mer ribozyme strandA 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleasesX-ray diffraction2.82008-05-20
223I2U|1|C5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10X-ray diffraction2.82009-11-03
233I2R|1|C5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'Crystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9X-ray diffraction2.82009-11-03

Release history

Release3.51
Date2018-12-07

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SPDBTitleMethodResolutionLength
1
3GS8|1|D+3GS8|1|C+3GS8|1|A+3GS8|1|B
An all-RNA hairpin ribozyme A38N1dA38 variant with a transition-state mimic substrate strandX-RAY DIFFRACTION2.8519
2
3GS1|1|D+3GS1|1|C+3GS1|1|A+3GS1|1|B
An all-RNA Hairpin Ribozyme with mutation A38N1dAX-RAY DIFFRACTION2.8519
3
2NPY|1|D+2NPY|1|C+2NPY|1|A+2NPY|1|B
Crystal Structure of a junctioned hairpin ribozyme incorporating 9atom linker and 2'-deoxy 2'-amino U at A-1X-RAY DIFFRACTION2.6519
4
2BCZ|1|D+2BCZ|1|C+2BCZ|1|A+2BCZ|1|B
Crystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8I, 2'deoxy A-1)X-RAY DIFFRACTION2.419
5
4G6R|1|D+4G6R|1|C+4G6R|1|A+4G6R|1|B
Minimal Hairpin Ribozyme in the Transition State with G8I VariationX-RAY DIFFRACTION2.8319
6
1ZFX|1|D+1ZFX|1|C+1ZFX|1|A+1ZFX|1|B
The Structure of a minimal all-RNA Hairpin Ribozyme with the mutant G8U at the cleavage siteX-RAY DIFFRACTION2.3819
7
1ZFV|1|D+1ZFV|1|C+1ZFV|1|A+1ZFV|1|B
The structure of an all-RNA minimal Hairpin Ribozyme with Mutation G8A at the cleavage siteX-RAY DIFFRACTION2.419
8
2FGP|1|D+2FGP|1|C+2FGP|1|A+2FGP|1|B
Crystal structure of a minimal, all RNA hairpin ribozyme with modifications (g8dap, u39c) at ph 8.6X-RAY DIFFRACTION2.419
9
2P7F|1|D+2P7F|1|C+2P7F|1|A+2P7F|1|B
The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small RibozymeX-RAY DIFFRACTION2.3519
10
2P7D|1|D+2P7D|1|C+2P7D|1|P
A Minimal, 'Hinged' Hairpin Ribozyme Construct Solved with Mimics of the Product Strands at 2.25 Angstroms ResolutionX-RAY DIFFRACTION2.2519
11
2P7E|1|D+2P7E|1|C+2P7E|1|P
Vanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State StabilizationX-RAY DIFFRACTION2.0519
12
3I2U|1|C
Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10X-RAY DIFFRACTION2.819
13
3I2R|1|C
Crystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9X-RAY DIFFRACTION2.819
14
3CQS|1|C
A 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleasesX-RAY DIFFRACTION2.819
15
3I2Q|1|C
Crystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A9X-RAY DIFFRACTION2.919
16
3I2S|1|C
Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10X-RAY DIFFRACTION2.7519
17
1ZFT|1|D+1ZFT|1|C+1ZFT|1|A+1ZFT|1|B
The crystal structure of an all-RNA minimal Hairpin Ribozyme with mutant G8I at the cleavage siteX-RAY DIFFRACTION2.3319
18
2OUE|1|D+2OUE|1|C+2OUE|1|A+2OUE|1|B
Crystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolutionX-RAY DIFFRACTION2.0519
19
1X9C|1|D+1X9C|1|C+1X9C|1|A+1X9C|1|B
An all-RNA Hairpin Ribozyme with mutation U39CX-RAY DIFFRACTION2.1919
20
2BCY|1|D+2BCY|1|C+2BCY|1|A+2BCY|1|B
Crystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8MTU)X-RAY DIFFRACTION2.719
21
2D2L|1|D+2D2L|1|C+2D2L|1|A+2D2L|1|B
Crystal Structure of a minimal, all-RNA hairpin ribozyme with a propyl linker (C3) at position U39X-RAY DIFFRACTION2.518
22
2D2K|1|D+2D2K|1|C+2D2K|1|A+2D2K|1|B
Crystal Structure of a minimal, native (U39) all-RNA hairpin ribozymeX-RAY DIFFRACTION2.6522
23
3CR1|1|C
crystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2X-RAY DIFFRACTION2.2519

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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