HL_3G6E_034

3D structure

PDB id

3G6E (explore in PDB, NAKB, or RNA 3D Hub)

Description

Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit

Experimental method

X-RAY DIFFRACTION

Resolution

2.7 Å

Loop

Sequence

GUGAGAACC

Length

9 nucleotides

Bulged bases

None detected

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_3G6E_034 not in the Motif Atlas

Homologous match to HL_4V9F_034

Geometric discrepancy: 0.0404

The information below is about HL_4V9F_034

Detailed Annotation

T-loop with 2 stacked bulged bases

Broad Annotation

T-loop

Motif group

HL_33597.1

Basepair signature

cWW-tWH-F-F-F-F-F

Number of instances in this motif group

96

Unit IDs

3G6E|1|0|G|1387
3G6E|1|0|U|1388
3G6E|1|0|G|1389
3G6E|1|0|A|1390
3G6E|1|0|G|1391
3G6E|1|0|A|1392
3G6E|1|0|A|1393
3G6E|1|0|C|1394
3G6E|1|0|C|1395

Current chains

Chain 0

23S ribosomal RNA

Nearby chains

Chain P

50S ribosomal protein L19e

Chain R

50S ribosomal protein L22P