HL_4OO8_009

3D structure

PDB id

4OO8 (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA

Experimental method

X-RAY DIFFRACTION

Resolution

2.5 Å

Loop

Sequence

UUGAAAAA

Length

8 nucleotides

Bulged bases

None detected

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

HL_4OO8_009 not in the Motif Atlas

Geometric match to HL_2IL9_007

Geometric discrepancy: 0.2117

The information below is about HL_2IL9_007

Detailed Annotation

GNRA with near cWW

Broad Annotation

GNRA with near cWW

Motif group

HL_82182.1

Basepair signature

cWW-F-F-F-F-F-F

Number of instances in this motif group

21

Unit IDs

4OO8|1|B|U|71
4OO8|1|B|U|72
4OO8|1|B|G|73
4OO8|1|B|A|74
4OO8|1|B|A|75
4OO8|1|B|A|76
4OO8|1|B|A|77
4OO8|1|B|A|78

Current chains

Chain B

RNA (97-MER)

Nearby chains

Chain A

CRISPR-associated endonuclease Cas9/Csn1

Chain D

CRISPR-associated endonuclease Cas9/Csn1