J5_10PX_012

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

CAG*CGUGC*GAG*CA*UG

Length

15 nucleotides

Bulged bases

10PX|1|2A|A|532, 10PX|1|2A|U|562

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J5_10PX_012 not in the Motif Atlas

Homologous match to J5_7A0S_003

Geometric discrepancy: 0.1271

The information below is about J5_7A0S_003

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

J5_43153.6

Basepair signature

cWW-cWW-cWW-F-cWW-cWW-cWW

Number of instances in this motif group

5

Unit IDs

10PX|1|2A|C|531
10PX|1|2A|A|532
10PX|1|2A|G|533
*
10PX|1|2A|C|560
10PX|1|2A|G|561
10PX|1|2A|U|562
10PX|1|2A|G|563
10PX|1|2A|C|564
*
10PX|1|2A|G|577
10PX|1|2A|A|578
10PX|1|2A|G|579
*
10PX|1|2A|C|1261
10PX|1|2A|A|1262
*
10PX|1|2A|U|2017
10PX|1|2A|G|2018

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 25

50S ribosomal protein L32

Chain 2F

50S ribosomal protein L4

Chain 2U

50S ribosomal protein L20

Chain 2V

50S ribosomal protein L21

Chain 2W

50S ribosomal protein L22