Structure title
Structure of the human 48S initiation complex in open state (h48S AUG open)
Authors
Yi, S.-H., Petrychenko, V., Schliep, J.E., Goyal, A., Linden, A., Chari, A., Urlaub, H., Stark, H., Rodnina, M.V., Adio, S., Fischer, N.
Release date
2022-05-11
Experimental technique
ELECTRON MICROSCOPY
Resolution
4.7 Å
Chains
3 RNA chains from Homo sapiens
50 other chains
Nucleic acid compounds
mRNA, 18S rRNA, Initiator Met-tRNA-i
Other compounds
Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit K, Eukaryotic translation initiation factor 3 subunit F, Eukaryotic translation initiation factor 3 subunit L, Eukaryotic translation initiation factor 3 subunit M, Eukaryotic translation initiation factor 3 subunit H, 60S ribosomal protein L41, 40S ribosomal protein S11, 40S ribosomal protein S4, X isoform, 40S ribosomal protein S9, 40S ribosomal protein S23, 40S ribosomal protein S30, 40S ribosomal protein S7, 40S ribosomal protein S27, 40S ribosomal protein S13, 40S ribosomal protein S15a, 40S ribosomal protein S21, 40S ribosomal protein S2, 40S ribosomal protein S17, 40S ribosomal protein SA, 40S ribosomal protein S3a, 40S ribosomal protein S14, 40S ribosomal protein S26, 40S ribosomal protein S8, 40S ribosomal protein S6, 40S ribosomal protein S24, 40S ribosomal protein S5, 40S ribosomal protein S16, 40S ribosomal protein S3, 40S ribosomal protein S10, 40S ribosomal protein S15, Receptor of activated protein C kinase 1, 40S ribosomal protein S19, 40S ribosomal protein S25, 40S ribosomal protein S18, 40S ribosomal protein S20, 40S ribosomal protein S29, Ubiquitin-40S ribosomal protein S27a, 40S ribosomal protein S12, 40S ribosomal protein S28, Eukaryotic translation initiation factor 3 subunit G, Eukaryotic translation initiation factor 1, Eukaryotic translation initiation factor 1A, X-chromosomal, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit E, Eukaryotic translation initiation factor 3 subunit D, Eukaryotic translation initiation factor 3 subunit C

Pairwise Interactions

Interactions annotated by FR3D: View all

RNA 3D Motifs

In the current release of the RNA 3D Motif Atlas, 7QP6 contains:
  • 39 hairpin loops from 0 motif groups
  • 107 internal loops from 0 motif groups
  • 21 junction loops from 0 motif groups
More

3D Redundancy

7QP6 has chains which belong to the following equivalence classes in the current representative set:

Similar structures

None found
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