Structure title
Late-stage 48S Initiation Complex with eIF3 (LS48S-eIF3 IC) guided by the trans-RNA
Authors
Nguyen, T.T., Hashem, Y., Rocha, R.E.O., Boissier, F., Qian, S.B., Jia, L., Uematsu, S., Gu, Y., Shi, S.
Release date
2025-12-10
Experimental technique
ELECTRON MICROSCOPY
Resolution
2.9 Å
Chains
3 RNA chains from Oryctolagus cuniculus
48 other chains
Nucleic acid compounds
Initiator methionylated tRNA, 18S ribosomal RNA, Linear mRNA
Other compounds
Eukaryotic translation initiation factor 2 subunit 1, protein-synthesizing GTPase, 40S ribosomal protein SA, 40S ribosomal protein S3a, Small ribosomal subunit protein uS5, Ribosomal protein S3, 40S ribosomal protein S4, Ribosomal protein S5, Small ribosomal subunit protein eS6, 40S ribosomal protein S7, Small ribosomal subunit protein eS8, 40S ribosomal protein S9, Small ribosomal subunit protein eS10, 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, 40S ribosomal protein uS11, 40S ribosomal protein uS19, Ribosomal protein S16, 40S ribosomal protein eS17, 40S ribosomal protein uS13, 40S ribosomal protein eS19, 40S ribosomal protein uS10, 40S ribosomal protein S21, Ribosomal protein S15a, 40S ribosomal protein S23, 40S ribosomal protein S24, 40S ribosomal protein S26, 40S ribosomal protein S27, 40S ribosomal protein S28, 40S ribosomal protein S29, Ribosomal protein S27a, Small ribosomal subunit protein RACK1, 40S ribosomal protein S30, Eukaryotic translation initiation factor 1A, X-chromosomal, ATP binding cassette subfamily E member 1, 60S ribosomal protein L41, Eukaryotic translation initiation factor 3 subunit D, 40S ribosomal protein S25, Eukaryotic translation initiation factor 5, Eukaryotic translation initiation factor 3 subunit F, Eukaryotic translation initiation factor 3 subunit H, Eukaryotic translation initiation factor 3 subunit K, Eukaryotic translation initiation factor 3 subunit L, Eukaryotic translation initiation factor 3 subunit M, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit E, Eukaryotic translation initiation factor 3 subunit A

Pairwise Interactions

Interactions annotated by FR3D: View all

RNA 3D Motifs

In the current release of the RNA 3D Motif Atlas, 9H74 contains:
  • 36 hairpin loops from 0 motif groups
  • 100 internal loops from 0 motif groups
  • 23 junction loops from 0 motif groups
More

3D Redundancy

9H74 has chains which belong to the following equivalence classes in the current representative set:

Similar structures

9H6Y 6YAN 6YAL 6YAM 9CPA
Structures from NR_all_19534.5
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