#IFECompound(s)RNA source organismTitleMethodResolutionDate
14ZT0|1|D (rep)single-guide RNAStreptococcus pyogenesCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.92015-07-08
24ZT0|1|Bsingle-guide RNAStreptococcus pyogenesCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.92015-07-08
34ZT9|1|Dsingle-guide RNAStreptococcus pyogenesNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.12015-07-08
44ZT9|1|Bsingle-guide RNAStreptococcus pyogenesNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.12015-07-08
57S4X|1|BgRNACas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationELECTRON MICROSCOPY2.762022-03-02
66O0X|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.282019-07-10
77S4V|1|BgRNACas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationELECTRON MICROSCOPY3.282022-03-02
86O0Y|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.372019-07-10
96O0Z|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.32019-07-10
107S4U|1|BgRNACryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-pointELECTRON MICROSCOPY3.562022-03-02

Release history

Release3.220
Date2022-03-02

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_4.0_30925.2NR_4.0_30925.13.220(7) 6O0Z|1|B, 6O0Y|1|B, 6O0X|1|B, 4ZT9|1|D, 4ZT9|1|B, 4ZT0|1|D, 4ZT0|1|B(3) 7S4X|1|B, 7S4V|1|B, 7S4U|1|B(0)

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
14ZT9|1|DNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.172
24ZT0|1|DCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.972
34ZT0|1|BCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.972
44ZT9|1|BNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.172
56O0Y|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.3798
66O0X|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.2898
77S4V|1|BCas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationELECTRON MICROSCOPY3.2898
87S4X|1|BCas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationELECTRON MICROSCOPY2.7698
96O0Z|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.396
107S4U|1|BCryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-pointELECTRON MICROSCOPY3.5697